Benadryl and Ribasphere drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Benadryl (diphenhydramine hydrochloride) and Ribasphere (ribavirin). Common drug interactions include asthenia among females and rash among males.

The phase IV clinical study analyzes what interactions people have when they take Benadryl and Ribasphere. It is created by eHealthMe based on reports of 61 people who take the same drugs from the FDA, and is updated regularly.

What is Benadryl?

Benadryl has active ingredients of diphenhydramine hydrochloride. It is often used in allergies. eHealthMe is studying from 104,954 Benadryl users. Check the latest studies of Benadryl.

What is Ribasphere?

Ribasphere has active ingredients of ribavirin. It is often used in hepatitis c. eHealthMe is studying from 9,336 Ribasphere users. Check the latest studies of Ribasphere.

On Jul, 17, 2026

61 people who take Benadryl and Ribasphere together, and have interactions are studied.

Benadryl and Ribasphere drug interactions.

What are the common drug interactions of Benadryl and Ribasphere, by gender? *:

female:

Asthenia (weakness)
Depression
Dizziness
Palpitations (feelings or sensations that your heart is pounding or racing)
Vision blurred
Anaemia (lack of blood)
Diarrhoea
Vomiting
Alopecia (absence of hair from areas of the body)
Anxiety

male:

Rash
Fatigue (feeling of tiredness)
Dizziness
Pain
Anaemia (lack of blood)
Oedema mouth (swelling of mouth)
Oral pain
Pain in extremity
Swelling
Tinnitus (a ringing in the ears)

What are the common drug interactions of Benadryl and Ribasphere, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Influenza like illness

30-39:

n/a

40-49:

Blood pressure increased
Chest pain
Fatigue (feeling of tiredness)
Nausea (feeling of having an urge to vomit)
Anaemia (lack of blood)
Constipation
Diarrhoea
Dizziness
Gastric perforation (hole in stomach)
Headache (pain in head)

50-59:

Anaemia (lack of blood)
Diarrhoea
Pain
Alopecia (absence of hair from areas of the body)
Anxiety
Blood glucose decreased
Blood pressure increased
Bone pain
Depression
Dry skin

60+:

Haemorrhoids (a swollen vein or group of veins in the region of the anus)
Fatigue (feeling of tiredness)
Adnexa uteri mass (ovarian cysts)
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Angioedema (rapid swelling of the dermis)
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Atrophic vulvovaginitis (inflammation of the vulva)
Bone disorder
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Bundle branch block left (absence of transmission of electric impulses from the atrioventricular (av) bundle of his to the left ventricle)

What are the existing conditions these people have? *

Pain: 6 people, 9.84%
Muscle Aches (muscle pain): 4 people, 6.56%
Hypersensitivity: 4 people, 6.56%

* Approximation only. Some reports may have incomplete information.

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