Bendamustine hydrochloride and Paroxetine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Bendamustine hydrochloride (bendamustine hydrochloride) and Paroxetine (paroxetine hydrochloride). Common drug interactions include alanine aminotransferase increased among females and chills among males.

The phase IV clinical study analyzes what interactions people have when they take Bendamustine hydrochloride and Paroxetine. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.

What is Bendamustine hydrochloride?

Bendamustine hydrochloride has active ingredients of bendamustine hydrochloride. eHealthMe is studying from 9,169 Bendamustine hydrochloride users. Check the latest studies of Bendamustine hydrochloride.

What is Paroxetine?

Paroxetine has active ingredients of paroxetine hydrochloride. It is often used in stress and anxiety. eHealthMe is studying from 65,088 Paroxetine users. Check the latest studies of Paroxetine.



On Jul, 06, 2026

15 people who take Bendamustine hydrochloride and Paroxetine together, and have interactions are studied.

Bendamustine hydrochloride and Paroxetine drug interactions.

What are the common drug interactions of Bendamustine Hydrochloride and Paroxetine, by gender? *:

female:

  1. Alanine aminotransferase increased
  2. Aplasia pure red cell (type of anaemia affecting the precursors to red blood cells but not to white blood cells)
  3. Arthralgia (joint pain)
  4. Arthritis (form of joint disorder that involves inflammation of one or more joints)
  5. Arthropathy
  6. Aspartate aminotransferase increased
  7. Basal cell carcinoma (a skin cancer, it rarely metastasizes or kills)
  8. Blood parathyroid hormone decreased
  9. Breath sounds
  10. C-reactive protein increased

male:

  1. Chills (felling of cold)
  2. Febrile neutropenia (fever with reduced white blood cells)
  3. Oxygen saturation decreased
  4. Pneumonia
  5. Pyrexia (fever)

What are the common drug interactions of Bendamustine Hydrochloride and Paroxetine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Liver disorder (liver diseases)

50-59:

  1. Ascites (accumulation of fluid in the abdominal cavity)
  2. Colitis (inflammation of colon)
  3. Encephalopathy (functioning of the brain is affected by some agent or condition)
  4. Hepatitis fulminant (life-threatening condition defined by significantly impaired liver function)
  5. Hepatocellular injury (liver injury)
  6. Hyperbilirubinaemia (excess of bilirubin in the blood)
  7. Prothrombin time shortened
  8. Thrombocytopenia (decrease of platelets in blood)
  9. Venoocclusive disease (small veins in the liver are obstructed)
  10. Weight increased

60+:

  1. Pneumonia
  2. Chills (felling of cold)
  3. Aplasia pure red cell (type of anaemia affecting the precursors to red blood cells but not to white blood cells)
  4. Arthralgia (joint pain)
  5. Arthritis (form of joint disorder that involves inflammation of one or more joints)
  6. Arthropathy
  7. Aspartate aminotransferase increased
  8. Basal cell carcinoma (a skin cancer, it rarely metastasizes or kills)
  9. Blood parathyroid hormone decreased
  10. Breath sounds

What are the existing conditions these people have? *

  1. Burkitt Lymphoma (cancer of the lymphatic system): 11 people, 73.33%
  2. Depression: 6 people, 40.00%
  3. High Blood Pressure: 5 people, 33.33%
  4. Hyperuricaemia (level of uric acid in the blood that is abnormally high): 3 people, 20.00%
  5. Hyperlipidaemia (presence of excess lipids in the blood): 3 people, 20.00%
  6. Allergic Rhinitis: 3 people, 20.00%
  7. Insomnia (sleeplessness): 3 people, 20.00%
  8. Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 2 people, 13.33%
  9. Lymphoma (cancer that begins in immune system cells): 1 person, 6.67%
  10. Pain: 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Bendamustine hydrochloride and Paroxetine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Bendamustine hydrochloride:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Paroxetine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Bendamustine hydrochloride and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Paroxetine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on bendamustine hydrochloride and paroxetine hydrochloride (the active ingredients of Bendamustine hydrochloride and Paroxetine, respectively), and Bendamustine hydrochloride and Paroxetine (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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