Bendamustine hydrochloride and Zide drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Bendamustine hydrochloride (bendamustine hydrochloride) and Zide (hydrochlorothiazide). Common drug interactions include eating disorder among females and febrile neutropenia among males.

The phase IV clinical study analyzes what interactions people have when they take Bendamustine hydrochloride and Zide. It is created by eHealthMe based on reports of 92 people who take the same drugs from the FDA, and is updated regularly.

What is Bendamustine hydrochloride?

Bendamustine hydrochloride has active ingredients of bendamustine hydrochloride. eHealthMe is studying from 9,169 Bendamustine hydrochloride users. Check the latest studies of Bendamustine hydrochloride.

What is Zide?

Zide has active ingredients of hydrochlorothiazide. It is often used in high blood pressure. eHealthMe is studying from 183,246 Zide users. Check the latest studies of Zide.



On Jul, 31, 2026

92 people who take Bendamustine hydrochloride and Zide together, and have interactions are studied.

Bendamustine hydrochloride and Zide drug interactions.

What are the common drug interactions of Bendamustine Hydrochloride and Zide, by gender? *:

female:

  1. Eating disorder
  2. Febrile neutropenia (fever with reduced white blood cells)
  3. Haemoglobin decreased
  4. Hypoaesthesia (reduced sense of touch or sensation)
  5. Hypogammaglobulinaemia (an abnormally low concentration of gamma globulin in the blood and increased risk of infection)
  6. Immune system disorder
  7. Infective exacerbation of chronic obstructive airways disease (severe infective lung disease with chronic obstructive airways disease)
  8. Nasal dryness (dry nose)
  9. Nasal ulcer (ulcer of nose)
  10. Oropharyngeal pain

male:

  1. Febrile neutropenia (fever with reduced white blood cells)
  2. Blood pressure decreased
  3. Jc virus infection
  4. Mantle cell lymphoma recurrent (cancer of lymphocytes, a type of white blood cell- recurrent)
  5. Nervous system disorder (a general class of medical conditions affecting the nervous system)
  6. Pneumonitis (inflammation of the walls of the alveoli in the lungs)
  7. Cd4 lymphocytes decreased
  8. Dysphonia (speech disorder attributable to a disorder of phonation)
  9. Headache (pain in head)
  10. Hypogammaglobulinaemia (an abnormally low concentration of gamma globulin in the blood and increased risk of infection)

What are the common drug interactions of Bendamustine Hydrochloride and Zide, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Disease progression
  2. Jc virus infection
  3. Mantle cell lymphoma recurrent (cancer of lymphocytes, a type of white blood cell- recurrent)
  4. Nervous system disorder (a general class of medical conditions affecting the nervous system)
  5. Pyrexia (fever)

60+:

  1. Febrile neutropenia (fever with reduced white blood cells)
  2. Blood pressure decreased
  3. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  4. Pneumonitis (inflammation of the walls of the alveoli in the lungs)
  5. Cd4 lymphocytes decreased
  6. Dysphonia (speech disorder attributable to a disorder of phonation)
  7. Myelodysplastic syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged)
  8. Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
  9. Pneumonia primary atypical (primary atypical pneumonia which were probably caused by mycoplasma pneumoniae)
  10. Rash pruritic (redness with itching)

What are the existing conditions these people have? *

  1. Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 21 people, 22.83%
  2. Upper-Airway Cough Syndrome: 11 people, 11.96%
  3. Stress And Anxiety: 11 people, 11.96%
  4. Seasonal Allergy (allergic condition due to certain season): 11 people, 11.96%
  5. Nausea (feeling of having an urge to vomit): 11 people, 11.96%
  6. Haemorrhoids (a swollen vein or group of veins in the region of the anus): 11 people, 11.96%
  7. Cough: 11 people, 11.96%
  8. Mantle Cell Lymphoma (cancer of lymphocytes, a type of white blood cell): 9 people, 9.78%

* Approximation only. Some reports may have incomplete information.

Do you take Bendamustine hydrochloride and Zide?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Bendamustine hydrochloride and Zide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Bendamustine hydrochloride:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Zide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Bendamustine hydrochloride and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Zide and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on bendamustine hydrochloride and hydrochlorothiazide (the active ingredients of Bendamustine hydrochloride and Zide, respectively), and Bendamustine hydrochloride and Zide (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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