Bendamustine and Escitalopram drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Bendamustine (bendamustine) and Escitalopram (escitalopram oxalate). Common drug interactions include agranulocytosis among females and disease progression among males.
The phase IV clinical study analyzes what interactions people have when they take Bendamustine and Escitalopram. It is created by eHealthMe based on reports of 63 people who take the same drugs from the FDA, and is updated regularly.
What is Bendamustine?
Bendamustine has active ingredients of bendamustine. eHealthMe is studying from 9,508 Bendamustine users. Check the latest studies of Bendamustine.
What is Escitalopram?
Escitalopram has active ingredients of escitalopram oxalate. It is often used in depression. eHealthMe is studying from 78,080 Escitalopram users. Check the latest studies of Escitalopram.
63 people who take Bendamustine and Escitalopram together, and have interactions are studied.

What are the common drug interactions of Bendamustine and Escitalopram, by gender? *:
female:
- Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
- Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)
- Disease progression
- Electrocardiogram qt prolonged
- Hypertensive cardiomyopathy (heart disease caused by high blood pressure)
- Hypokalaemia (low potassium)
- Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood)
- Pyrexia (fever)
- Syncope (loss of consciousness with an inability to maintain postural tone)
- Ventricular tachycardia (rapid heartbeat that originates in one of the lower chambers (the ventricles) of the heart)
male:
- Disease progression
- C-reactive protein increased
- Anaphylactoid reaction (type of anaphylaxis that does not involve an allergic reaction but is due to direct mast cell degranulation)
- Lymphopenia (an abnormally low level of lymphocytes in the blood)
- Nasopharyngitis (inflammation of the nasopharynx)
- Pyrexia (fever)
- Neck pain
- Pain
- Neck mass (mass in neck)
- Neutropenic sepsis (whole body infection is caused by a condition in which the number of white blood cells (called neutrophils) in the blood is low. neutrophils help the body to fight infection)
What are the common drug interactions of Bendamustine and Escitalopram, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
40-49:
n/a
50-59:
- Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)
- Disease progression
- Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
- Lymphopenia (an abnormally low level of lymphocytes in the blood)
- Neutropenia (an abnormally low number of neutrophils)
- Chronic lymphocytic leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell))
- Drug ineffective
- Neoplasm progression (growth of tumour)
60+:
- Neutropenic sepsis (whole body infection is caused by a condition in which the number of white blood cells (called neutrophils) in the blood is low. neutrophils help the body to fight infection)
- Pyrexia (fever)
- Abdominal pain upper
- Disease progression
- Malignant neoplasm progression (cancer tumour came back)
- Anaphylactoid reaction (type of anaphylaxis that does not involve an allergic reaction but is due to direct mast cell degranulation)
- Drug hypersensitivity
- Lymphopenia (an abnormally low level of lymphocytes in the blood)
- Neurotoxicity (when the exposure to natural or artificial toxic substances, which are called neurotoxins, alters the normal activity of the nervous system)
- Post procedural haemorrhage (post procedural bleeding)
What are the existing conditions these people have? *
- Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 37 people, 58.73%
- Burkitt Lymphoma (cancer of the lymphatic system): 18 people, 28.57%
- Rhinitis (a medical term for irritation and inflammation of the mucous membrane inside the nose): 12 people, 19.05%
- Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 11 people, 17.46%
- Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 10 people, 15.87%
- Immunodeficiency: 9 people, 14.29%
- Dyslipidaemia (abnormal amount of lipids): 9 people, 14.29%
- Richter's Syndrome (hairy cell cancer changes in fast growing b cell cancer tumour): 8 people, 12.70%
- High Blood Pressure: 8 people, 12.70%
- Post Herpetic Neuralgia (neuralgia caused by the varicella zoster virus): 5 people, 7.94%
* Approximation only. Some reports may have incomplete information.
Do you take Bendamustine and Escitalopram?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Bendamustine (9,508 reports)
- Escitalopram (78,080 reports)
Browse all drug interactions of Bendamustine and Escitalopram:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Bendamustine:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Escitalopram:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Bendamustine and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Escitalopram and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- O’Brien FE, O’Connor RM, Clarke G, Donovan MD, Dinan TG, Griffin BT, Cryan JF, "The P-glycoprotein inhibitor cyclosporin A differentially influences behavioural and neurochemical responses to the antidepressant escitalopram", Behavioural brain research, 2014 Mar .
- O’Brien FE, O’Connor RM, Clarke G, Donovan MD, Dinan TG, Griffin BT, Cryan JF, "The P-glycoprotein inhibitor cyclosporin A differentially influences behavioural and neurochemical responses to the antidepressant escitalopram", Behavioural brain research, 2014 Mar .
How the study uses the data?
The study uses data from the FDA. It is based on bendamustine and escitalopram oxalate (the active ingredients of Bendamustine and Escitalopram, respectively), and Bendamustine and Escitalopram (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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