Bendamustine and Zyloprim drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Bendamustine (bendamustine) and Zyloprim (allopurinol). Common drug interactions include atrial fibrillation among females and hypercalcaemia among males.
The phase IV clinical study analyzes what interactions people have when they take Bendamustine and Zyloprim. It is created by eHealthMe based on reports of 22 people who take the same drugs from the FDA, and is updated regularly.
What is Bendamustine?
Bendamustine has active ingredients of bendamustine. eHealthMe is studying from 9,508 Bendamustine users. Check the latest studies of Bendamustine.
What is Zyloprim?
Zyloprim has active ingredients of allopurinol. It is often used in gout. eHealthMe is studying from 5,638 Zyloprim users. Check the latest studies of Zyloprim.
22 people who take Bendamustine and Zyloprim together, and have interactions are studied.

What are the common drug interactions of Bendamustine and Zyloprim, by gender? *:
female:
- Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
- Diarrhoea
- Drug intolerance (drug sensitivity)
- Neutropenia (an abnormally low number of neutrophils)
- Aortic disorder
- Aortic valve incompetence
- Constipation
- Decreased appetite
- Disease progression
- Drug hypersensitivity
male:
- Hypercalcaemia (elevated calcium (ca+) level in the blood)
- Neutropenia (an abnormally low number of neutrophils)
- Respiratory failure (inadequate gas exchange by the respiratory system)
- Anaemia (lack of blood)
- B-cell lymphoma (blood cancer affecting b cells)
- Blood immunoglobulin m increased
- Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)
- Death
- Epistaxis (bleed from the nose)
- Hyperlipidaemia (presence of excess lipids in the blood)
What are the common drug interactions of Bendamustine and Zyloprim, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
- Blood immunoglobulin m increased
- Death
- Hyperviscosity syndrome (a condition in which blood is not able to flow freely through your arteries)
60+:
- Aortic disorder
- Aortic valve incompetence
- Lymphadenopathy (disease or enlargement of lymph nodes)
- Neuropathy peripheral (surface nerve damage)
- Pyrexia (fever)
- Rash macular (small, flat red spots)
- Sinus rhythm (normal beating of the heart)
- Thyroid mass
- Hypophosphataemia (electrolyte disturbance in which there is an abnormally low level of phosphate in the blood)
- Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)
What are the existing conditions these people have? *
- Nausea (feeling of having an urge to vomit): 10 people, 45.45%
- Wheezing (a high-pitched whistling sound made while you breath): 6 people, 27.27%
- Nausea And Vomiting: 6 people, 27.27%
- Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 6 people, 27.27%
- Waldenstrom's Macroglobulinaemia (cancer affects small lymphocytes (white blood cells)): 4 people, 18.18%
- Pain: 4 people, 18.18%
- Mantle Cell Lymphoma (cancer of lymphocytes, a type of white blood cell): 3 people, 13.64%
- Erection Problems: 3 people, 13.64%
- Constipation: 3 people, 13.64%
- Chronic Lymphocytic Leukaemia Recurrent (repeated cancer of blood cells known as lymphocytes): 3 people, 13.64%
* Approximation only. Some reports may have incomplete information.
Do you take Bendamustine and Zyloprim?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Bendamustine (9,508 reports)
- Zyloprim (5,638 reports)
Browse all drug interactions of Bendamustine and Zyloprim:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Bendamustine:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Zyloprim:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Bendamustine and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Zyloprim and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on bendamustine and allopurinol (the active ingredients of Bendamustine and Zyloprim, respectively), and Bendamustine and Zyloprim (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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