Isoniazid and Carbamazepine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Isoniazid (isoniazid) and Carbamazepine (carbamazepine). Common drug interactions include tuberculosis skin test positive among females and hyponatraemia among males.

The phase IV clinical study analyzes what interactions people have when they take Isoniazid and Carbamazepine. It is created by eHealthMe based on reports of 56 people who take the same drugs from the FDA, and is updated regularly.

What is Isoniazid?

Isoniazid has active ingredients of isoniazid. It is often used in tuberculosis. eHealthMe is studying from 20,174 Isoniazid users. Check the latest studies of Isoniazid.

What is Carbamazepine?

Carbamazepine has active ingredients of carbamazepine. It is often used in epilepsy. eHealthMe is studying from 44,628 Carbamazepine users. Check the latest studies of Carbamazepine.

On Jul, 10, 2026

56 people who take Isoniazid and Carbamazepine together, and have interactions are studied.

Isoniazid and Carbamazepine drug interactions.

What are the common drug interactions of Isoniazid and Carbamazepine, by gender? *:

female:

Tuberculosis skin test positive
Viiith nerve lesion
Weakness
White blood cell count decreased
Dizziness
Gait disturbance
Ataxia (loss of full control of bodily movements)
Confusional state
Drug level above therapeutic
Febrile neutropenia (fever with reduced white blood cells)

male:

Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Pyrexia (fever)
Psoriasis (immune-mediated disease that affects the skin)
Vomiting
Abasia (inability to walk)
Abdominal pain upper
Anticonvulsant drug level above therapeutic
Arthralgia (joint pain)
Atypical pneumonia (acute respiratory disease marked by high fever and coughing)
Bronchopulmonary aspergillosis (lung disorder caused by aspergillus fungi)

What are the common drug interactions of Isoniazid and Carbamazepine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Seizure (abnormal excessive or synchronous neuronal activity in the brain)

10-19:

Hepatic failure (liver failure)
Asterixis (flapping tremor, or liver flap)
Depressed level of consciousness
Encephalopathy (functioning of the brain is affected by some agent or condition)
Jaundice (a yellowish pigmentation of the skin, the conjunctival membranes)
Somnolence (a state of near-sleep, a strong desire for sleep)
Acute hepatic failure
Anticonvulsant drug level above therapeutic
Coagulation factor v level decreased
Drug ineffective

20-29:

Eating disorder
Delusion (a false belief or opinion)
Hallucination (an experience involving the perception of something not present)
Influenza
Myoclonus (a brief, involuntary twitching of a muscle or a group of muscles)
Nausea (feeling of having an urge to vomit)
Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)
Status epilepticus (a life-threatening condition in which the brain is in a state of persistent seizure)
Tachypnoea (a condition of rapid breathing over 20 per minute)
Abasia (inability to walk)

30-39:

Dehydration (dryness resulting from the removal of water)
Fatigue (feeling of tiredness)
Somnolence (a state of near-sleep, a strong desire for sleep)
Abdominal pain upper
Asthenia (weakness)
Bronchopulmonary aspergillosis (lung disorder caused by aspergillus fungi)
Cough
Difficulty in walking
Eye pain
Headache (pain in head)

40-49:

Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Water intoxication (water poisoning)
Dizziness
Asthenia (weakness)
Gastrointestinal perforation (hole in the digestive tract)
Hypomania (a mild form of mania, marked by elation and hyperactivity)
Large intestine perforation (hole in large intestine)
Bipolar affective disorder
Lethargy (tiredness)
Muscle spasms (muscle contraction)

50-59:

Cholestasis (a condition where bile cannot flow from the liver to the duodenum)
Confusional state
Drug level above therapeutic
Febrile neutropenia (fever with reduced white blood cells)
Gait disturbance
Hypogammaglobulinaemia (an abnormally low concentration of gamma globulin in the blood and increased risk of infection)
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Hypovolaemia (a decreased volume of circulating blood in the body)
Lymphopenia (an abnormally low level of lymphocytes in the blood)
Mucosal inflammation (infection of mucous membrane)

60+:

Psoriasis (immune-mediated disease that affects the skin)
Acute hepatic failure
Arthralgia (joint pain)
Atypical pneumonia (acute respiratory disease marked by high fever and coughing)
Constipation
Erythrodermic psoriasis (generalized redness of the skin)
Hepatic encephalopathy (spectrum of neuropsychiatric abnormalities in patients with liver failure)
Pneumonia
Skin lesion

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 9 people, 16.07%
Pain: 6 people, 10.71%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 5 people, 8.93%
High Blood Pressure: 5 people, 8.93%
Oedema (fluid collection in tissue): 4 people, 7.14%
Lung Cancer - Non-Small Cell (lung cancer): 4 people, 7.14%
Dyspnea (difficult or laboured breathing): 4 people, 7.14%
Psychotic Disorder: 3 people, 5.36%
Psoriasis (immune-mediated disease that affects the skin): 3 people, 5.36%
Hiv Infection: 3 people, 5.36%

* Approximation only. Some reports may have incomplete information.

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