Benicar and Lescol drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Benicar (olmesartan medoxomil) and Lescol (fluvastatin sodium). Common drug interactions include abdominal discomfort among females and dyspnoea among males.

The phase IV clinical study analyzes what interactions people have when they take Benicar and Lescol. It is created by eHealthMe based on reports of 69 people who take the same drugs from the FDA, and is updated regularly.

What is Benicar?

Benicar has active ingredients of olmesartan medoxomil. It is often used in high blood pressure. eHealthMe is studying from 36,002 Benicar users. Check the latest studies of Benicar.

What is Lescol?

Lescol has active ingredients of fluvastatin sodium. It is often used in high blood cholesterol. eHealthMe is studying from 7,306 Lescol users. Check the latest studies of Lescol.



On Jul, 19, 2026

69 people who take Benicar and Lescol together, and have interactions are studied.

Benicar and Lescol drug interactions.

What are the common drug interactions of Benicar and Lescol, by gender? *:

female:

  1. Abdominal discomfort
  2. Abdominal pain
  3. Adverse event
  4. Alopecia (absence of hair from areas of the body)
  5. Arthropathy
  6. Asthma
  7. Blindness unilateral
  8. Blood urea increased
  9. Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi)
  10. Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)

male:

  1. Dyspnoea (difficult or laboured respiration)
  2. Malaise (a feeling of general discomfort or uneasiness)
  3. Dyspnoea paroxysmal nocturnal (respiratory distress that awakens patients from sleep)
  4. Limb discomfort (discomfort in leg)
  5. Loss of consciousness
  6. Skin discolouration (change of skin colour)
  7. Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
  8. Renal failure (kidney dysfunction)
  9. Renal injury (kidney injury)
  10. Joint injury

What are the common drug interactions of Benicar and Lescol, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Ankle fracture
  2. Arthritis (form of joint disorder that involves inflammation of one or more joints)
  3. Arthropathy
  4. Back disorder
  5. Bone disorder
  6. Bone pain
  7. Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
  8. Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)
  9. Cartilage injury
  10. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)

30-39:

n/a

40-49:

  1. Blood glucose decreased
  2. Foot fracture
  3. Localised infection (infection at the single location)
  4. Muscle spasms (muscle contraction)
  5. Hypotension (abnormally low blood pressure)
  6. Hypovolaemia (a decreased volume of circulating blood in the body)
  7. Middle insomnia (difficulty returning to sleep after awakening either in the middle of the night)
  8. Renal failure (kidney dysfunction)
  9. Sleep disorder
  10. Viral infection

50-59:

  1. Crying
  2. Dyspnoea (difficult or laboured respiration)
  3. Inflammation
  4. Neurosis (a class of functional mental disorders involving distress but neither delusions nor hallucinations)
  5. Pseudomonas infection (pseudomonas infection is caused by a bacterium, pseudomonas aeruginosa)
  6. Renal failure (kidney dysfunction)
  7. Renal failure acute (rapid kidney dysfunction)
  8. Renal failure chronic (long lasting kidney dysfunction)
  9. Screaming (a long loud piercing cry)
  10. Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)

60+:

  1. Drug ineffective
  2. Renal failure (kidney dysfunction)
  3. Migraine (headache)
  4. Wheezing (a high-pitched whistling sound made while you breath)
  5. Dehydration (dryness resulting from the removal of water)
  6. Dyspnoea paroxysmal nocturnal (respiratory distress that awakens patients from sleep)
  7. Limb discomfort (discomfort in leg)
  8. Loss of consciousness
  9. Skin discolouration (change of skin colour)
  10. Abdominal discomfort

What are the existing conditions these people have? *

  1. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 21 people, 30.43%
  2. Anaemia (lack of blood): 10 people, 14.49%
  3. Gastric Ulcer (stomach ulcer): 8 people, 11.59%
  4. Renal Disorder (kidney disease): 6 people, 8.70%
  5. Gout (uric acid crystals building up in the body): 6 people, 8.70%
  6. Pain: 5 people, 7.25%
  7. Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 5 people, 7.25%
  8. Type 2 Diabetes: 4 people, 5.80%
  9. Indigestion: 4 people, 5.80%
  10. Hyperlipidaemia (presence of excess lipids in the blood): 4 people, 5.80%

* Approximation only. Some reports may have incomplete information.

Do you take Benicar and Lescol?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Benicar and Lescol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Benicar:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Lescol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Benicar and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Lescol and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on olmesartan medoxomil and fluvastatin sodium (the active ingredients of Benicar and Lescol, respectively), and Benicar and Lescol (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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