Benicar and Rocaltrol drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Benicar (olmesartan medoxomil) and Rocaltrol (calcitriol). Common drug interactions include renal failure among females and dry skin among males.
The phase IV clinical study analyzes what interactions people have when they take Benicar and Rocaltrol. It is created by eHealthMe based on reports of 19 people who take the same drugs from the FDA, and is updated regularly.
What is Benicar?
Benicar has active ingredients of olmesartan medoxomil. It is often used in high blood pressure. eHealthMe is studying from 36,002 Benicar users. Check the latest studies of Benicar.
What is Rocaltrol?
Rocaltrol has active ingredients of calcitriol. It is often used in hypoparathyroidism. eHealthMe is studying from 7,562 Rocaltrol users. Check the latest studies of Rocaltrol.
19 people who take Benicar and Rocaltrol together, and have interactions are studied.

What are the common drug interactions of Benicar and Rocaltrol, by gender? *:
female:
- Renal failure (kidney dysfunction)
- Chronic kidney disease
- Blood glucose increased
- Hyperphosphataemia (electrolyte disturbance in which there is an abnormally elevated level of phosphate in the blood)
- Nephrogenic anaemia (anaemia due to kidney disease)
- Pitting oedema (skin discoloration)
- Bacterial infection
- Feeling hot
- Hyperglycaemia (high blood sugar)
- Hyperhidrosis (abnormally increased sweating)
male:
- Dry skin
- Joint range of motion decreased (disease of joint movement)
- Skin tightness
- Bradycardia (abnormally slow heart action)
- Chronic kidney disease
- Dyspnoea (difficult or laboured respiration)
- Electrocardiogram qt prolonged
- Formication (a sensation that exactly resembles that of small insects crawling on (or under) the skin)
- Hallucination (an experience involving the perception of something not present)
- Headache (pain in head)
What are the common drug interactions of Benicar and Rocaltrol, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Dry skin
- Joint range of motion decreased (disease of joint movement)
- Joint stiffness
- Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
- Pain
- Rash macular (small, flat red spots)
- Skin discolouration (change of skin colour)
- Skin hypertrophy (skin cells enlarges)
- Skin induration (an abnormally hard spot or area on the skin)
- Skin plaque (red, scaly patches to appear on the skin)
30-39:
- Blood glucose increased
- Hyperphosphataemia (electrolyte disturbance in which there is an abnormally elevated level of phosphate in the blood)
- Pitting oedema (skin discoloration)
40-49:
n/a
50-59:
- Chronic kidney disease
- Dyspnoea (difficult or laboured respiration)
- Formication (a sensation that exactly resembles that of small insects crawling on (or under) the skin)
- Hallucination (an experience involving the perception of something not present)
- Headache (pain in head)
- Hyperglycaemia (high blood sugar)
- Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
- Insomnia (sleeplessness)
- Malaise (a feeling of general discomfort or uneasiness)
- Nephrogenic anaemia (anaemia due to kidney disease)
60+:
- Renal failure (kidney dysfunction)
- Bacterial infection
- International normalised ratio increased
- Nephrogenic anaemia (anaemia due to kidney disease)
- Neutropenia (an abnormally low number of neutrophils)
- Rash
- Renal failure acute (rapid kidney dysfunction)
- Syncope (loss of consciousness with an inability to maintain postural tone)
- Throat irritation
- Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
What are the existing conditions these people have? *
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 26.32%
- Nausea (feeling of having an urge to vomit): 4 people, 21.05%
- Indigestion: 3 people, 15.79%
- Diabetes: 3 people, 15.79%
- Blood Pressure Abnormal: 3 people, 15.79%
- Blood Calcium Decreased: 3 people, 15.79%
- Insomnia (sleeplessness): 3 people, 15.79%
- Thyroid Diseases: 2 people, 10.53%
- Nausea And Vomiting: 2 people, 10.53%
- Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 2 people, 10.53%
* Approximation only. Some reports may have incomplete information.
Do you take Benicar and Rocaltrol?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Benicar and Rocaltrol:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Benicar:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Rocaltrol:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Benicar and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Rocaltrol and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on olmesartan medoxomil and calcitriol (the active ingredients of Benicar and Rocaltrol, respectively), and Benicar and Rocaltrol (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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