Benicar and Testim drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Benicar (olmesartan medoxomil) and Testim (testosterone). Common drug interactions include aortic calcification among females and erectile dysfunction among males.

The phase IV clinical study analyzes what interactions people have when they take Benicar and Testim. It is created by eHealthMe based on reports of 48 people who take the same drugs from the FDA, and is updated regularly.

What is Benicar?

Benicar has active ingredients of olmesartan medoxomil. It is often used in high blood pressure. eHealthMe is studying from 36,002 Benicar users. Check the latest studies of Benicar.

What is Testim?

Testim has active ingredients of testosterone. It is often used in testosterone. eHealthMe is studying from 5,453 Testim users. Check the latest studies of Testim.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 25, 2026

48 people who take Benicar and Testim together, and have interactions are studied.

What are the common drug interactions of Benicar and Testim, by gender? *:

female:

Aortic calcification (aortic calcification sign of heart valve disease)
Arrhythmia (irregular heartbeat)
Arteriosclerosis coronary artery (thickening and hardening of arteries- coronary artery)
Asthenia (weakness)
Atelectasis (partial or complete collapse of the lung)
Biliary colic
Bladder disorder
Blood glucose increased
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Carotid arteriosclerosis (plaque deposition in artery)

male:

Erectile dysfunction
Fatigue (feeling of tiredness)
Discomfort
Dysphagia (a condition in which swallowing is difficult or painful)
Headache (pain in head)
Lung neoplasm (tumour of lung)
Lymphadenopathy (disease or enlargement of lymph nodes)
Lymphadenopathy mediastinal (an enlargement of the lymph nodes in the part of the chest that separates the lungs)
Metastases to adrenals (cancer spreads to adrenal gland of kidney)
Metastases to bone (cancer spreads to bone)

What are the common drug interactions of Benicar and Testim, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Chronic kidney disease
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Bone density decreased
Emotional distress
Osteopenia (a condition where bone mineral density is lower than normal)
Osteoporosis (bones weak and more likely to break)
Pain
Renal impairment (severely reduced kidney function)
Aldolase increased

50-59:

Arteriosclerosis (thickening and hardening of arteries)
Blood pressure fluctuation
Chest discomfort
Chronic kidney disease
Conversion disorder (neurological symptoms, such as numbness, blindness, paralysis, or fits without a definable organic cause)
Cough
Decreased appetite
Depression
Dilatation ventricular
Dysarthria (speech disorder)

60+:

Fatigue (feeling of tiredness)
Abdominal pain
Dysphagia (a condition in which swallowing is difficult or painful)
Headache (pain in head)
Lymphadenopathy (disease or enlargement of lymph nodes)
Lymphadenopathy mediastinal (an enlargement of the lymph nodes in the part of the chest that separates the lungs)
Metastases to adrenals (cancer spreads to adrenal gland of kidney)
Metastases to bone (cancer spreads to bone)
Metastases to lung (cancer spreads to lung)
Metastases to neck (cancer spreads to neck)

What are the existing conditions these people have? *

Neoplasm Malignant (cancer tumour): 16 people, 33.33%
Blood Testosterone Decreased: 12 people, 25.00%
Pain: 4 people, 8.33%
Hiv Infection: 4 people, 8.33%
Diabetes: 4 people, 8.33%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 3 people, 6.25%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 6.25%
Erection Problems: 3 people, 6.25%
Depression: 3 people, 6.25%
Back Pain: 3 people, 6.25%

* Approximation only. Some reports may have incomplete information.

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