Benlysta and Klonopin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Benlysta (belimumab) and Klonopin (clonazepam). Common drug interactions include lung disorder among females and confusional state among males.

The phase IV clinical study analyzes what interactions people have when they take Benlysta and Klonopin. It is created by eHealthMe based on reports of 67 people who take the same drugs from the FDA, and is updated regularly.

What is Benlysta?

Benlysta has active ingredients of belimumab. It is often used in systemic lupus erythematosus. eHealthMe is studying from 23,528 Benlysta users. Check the latest studies of Benlysta.

What is Klonopin?

Klonopin has active ingredients of clonazepam. It is often used in stress and anxiety. eHealthMe is studying from 65,112 Klonopin users. Check the latest studies of Klonopin.



On Jul, 20, 2026

67 people who take Benlysta and Klonopin together, and have interactions are studied.

Benlysta and Klonopin drug interactions.

What are the common drug interactions of Benlysta and Klonopin, by gender? *:

female:

  1. Lung disorder (lung disease)
  2. Muscle tightness
  3. Oedema peripheral (superficial swelling)
  4. Oxygen saturation decreased
  5. Paraesthesia oral (sensation of tingling, tickling, prickling, pricking, or burning of a person's oral with no apparent long-term physical effect)
  6. Pharyngeal oedema (abnormal accumulation of fluid in the cavities and intercellular spaces of the pharyngeal)
  7. Pleurisy (inflammation of the pleurae, which causes pain when breathing)
  8. Psychotic disorder
  9. Sjogren's syndrome (a disease that causes dryness in the mouth and eyes)
  10. Swollen tongue (swelling of tongue)

male:

  1. Confusional state
  2. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
  3. Adverse drug reaction
  4. Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
  5. Arthralgia (joint pain)
  6. Back disorder
  7. Bone disorder
  8. Bone lesion (bone with abnormalities. bone lesions can result from growth formations, infections, or injuries)
  9. Chest pain
  10. Cough

What are the common drug interactions of Benlysta and Klonopin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

  1. Dizziness
  2. Drug administration error
  3. Flushing (the warm, red condition of human skin)
  4. Headache (pain in head)

10-19:

n/a

20-29:

  1. Blood pressure decreased

30-39:

  1. Dizziness
  2. Abdominal pain
  3. Breast mass
  4. Chest discomfort
  5. Chills (felling of cold)
  6. Depression
  7. Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
  8. Dyspnoea (difficult or laboured respiration)
  9. Heart rate increased
  10. Insomnia (sleeplessness)

40-49:

  1. Headache (pain in head)
  2. Influenza like illness
  3. Pyrexia (fever)
  4. Erythema (redness of the skin)
  5. Pain in extremity
  6. Throat irritation
  7. Peripheral swelling
  8. Arthralgia (joint pain)
  9. Chest pain
  10. Decreased appetite

50-59:

  1. Urinary tract infection
  2. Vitamin b12 decreased
  3. Weight increased
  4. Headache (pain in head)
  5. Rhinorrhoea (watery mucus discharge from the nose)
  6. Fatigue (feeling of tiredness)
  7. Insomnia (sleeplessness)
  8. Asthma
  9. Diarrhoea
  10. Anaphylactic reaction (serious allergic reaction)

60+:

  1. Nausea (feeling of having an urge to vomit)
  2. Dizziness
  3. Fall
  4. Headache (pain in head)
  5. Incontinence (lack of moderation or self-control)
  6. Somnambulism (sleep walking)
  7. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  8. Adverse drug reaction
  9. Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
  10. Back disorder

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Benlysta and Klonopin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Benlysta:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Klonopin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Benlysta and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Klonopin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on belimumab and clonazepam (the active ingredients of Benlysta and Klonopin, respectively), and Benlysta and Klonopin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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