Benzaclin and Zofran drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Benzaclin (benzoyl peroxide; clindamycin phosphate) and Zofran (ondansetron hydrochloride). Common drug interactions include chronic kidney disease among females and dermatitis among males.

The phase IV clinical study analyzes what interactions people have when they take Benzaclin and Zofran. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.

What is Benzaclin?

Benzaclin has active ingredients of benzoyl peroxide; clindamycin phosphate. It is often used in acne. eHealthMe is studying from 477 Benzaclin users. Check the latest studies of Benzaclin.

What is Zofran?

Zofran has active ingredients of ondansetron hydrochloride. It is often used in nausea. eHealthMe is studying from 94,987 Zofran users. Check the latest studies of Zofran.

On Jul, 19, 2026

16 people who take Benzaclin and Zofran together, and have interactions are studied.

What are the common drug interactions of Benzaclin and Zofran, by gender? *:

female:

Chronic kidney disease
Injury
Pain
Renal failure (kidney dysfunction)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Biliary dyskinesia (motility disorder that affects the gallbladder and sphincter of oddi)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)
Decreased appetite

male:

Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
Mucosal inflammation (infection of mucous membrane)
Malignant neoplasm progression (cancer tumour came back)
Obstructive airways disorder (a progressive disease that makes it hard to breathe)
Poor quality sleep
Somnolence (a state of near-sleep, a strong desire for sleep)
Tonsillar hypertrophy (enlargement of the tonsils)
Urticaria (rash of round, red welts on the skin that itch intensely)
Cellulitis (infection under the skin)
Sinusitis (inflammation of sinus)

What are the common drug interactions of Benzaclin and Zofran, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Circadian rhythm sleep disorder (family of sleep disorders affecting, among other things, the timing of sleep)
Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)
Dyspepsia (indigestion)
Haematocrit decreased
Haemoglobin decreased
Injury
Insomnia (sleeplessness)
Obstructive airways disorder (a progressive disease that makes it hard to breathe)
Pain
Poor quality sleep

20-29:

Urticaria (rash of round, red welts on the skin that itch intensely)

30-39:

n/a

40-49:

Chronic kidney disease
Nephrogenic anaemia (anaemia due to kidney disease)
Renal failure (kidney dysfunction)

50-59:

Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
Mucosal inflammation (infection of mucous membrane)
Malignant neoplasm progression (cancer tumour came back)

60+:

Cellulitis (infection under the skin)
Sinusitis (inflammation of sinus)
Injury
Pain
Sputum increased
Sputum purulent
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Biliary dyskinesia (motility disorder that affects the gallbladder and sphincter of oddi)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)

What are the existing conditions these people have? *

Pain: 6 people, 37.50%
Constipation: 4 people, 25.00%
Diabetes: 3 people, 18.75%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 18.75%
Oral Pain: 3 people, 18.75%
Oral Cancer (mouth cancer): 3 people, 18.75%
Immunodeficiency Common Variable: 3 people, 18.75%
High Blood Pressure: 2 people, 12.50%
Hypersensitivity: 2 people, 12.50%
Dermatitis Atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder): 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

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