Benzonatate and Ocaliva drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Benzonatate (benzonatate) and Ocaliva (obeticholic acid). Common drug interactions include infusion site pain among females and dysphonia among males.

The phase IV clinical study analyzes what interactions people have when they take Benzonatate and Ocaliva. It is created by eHealthMe based on reports of 31 people who take the same drugs from the FDA, and is updated regularly.

What is Benzonatate?

Benzonatate has active ingredients of benzonatate. It is often used in cough. eHealthMe is studying from 17,274 Benzonatate users. Check the latest studies of Benzonatate.

What is Ocaliva?

Ocaliva has active ingredients of obeticholic acid. eHealthMe is studying from 6,919 Ocaliva users. Check the latest studies of Ocaliva.

On Aug, 12, 2026

31 people who take Benzonatate and Ocaliva together, and have interactions are studied.

Benzonatate and Ocaliva drug interactions.

What are the common drug interactions of Benzonatate and Ocaliva, by gender? *:

female:

Infusion site pain
Injection site pain
Localised infection (infection at the single location)
Bronchitis viral (inflammation of the mucous membrane in the bronchial tubes due to infection with streptococcus pneumoniae)
Dyspnoea (difficult or laboured respiration)
Sinusitis (inflammation of sinus)
Arrhythmia (irregular heartbeat)
Biliary dilatation
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Haemoperitoneum (presence of blood in the peritoneal cavity)

male:

Dysphonia (speech disorder attributable to a disorder of phonation)
Cardiac failure

What are the common drug interactions of Benzonatate and Ocaliva, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Headache (pain in head)
Infusion site discomfort
Infusion site infection
Infusion site pain
Neuropathy peripheral (surface nerve damage)
Oedema (fluid collection in tissue)
Pain in jaw
Dyspnoea (difficult or laboured respiration)

50-59:

Blindness unilateral
Optic nerve injury
Alopecia (absence of hair from areas of the body)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Constipation
Fatigue (feeling of tiredness)
Haemorrhagic stroke (stroke caused by the rupture of a blood vessel in the brain)
Hemiparesis (weakness on one side of the body)
Hypoaesthesia (reduced sense of touch or sensation)
Lethargy (tiredness)

60+:

Arrhythmia (irregular heartbeat)
Biliary dilatation
Dysphonia (speech disorder attributable to a disorder of phonation)
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Fatigue (feeling of tiredness)
Haemoperitoneum (presence of blood in the peritoneal cavity)
Post procedural haemorrhage (post procedural bleeding)
Pruritus (severe itching of the skin)
Somnolence (a state of near-sleep, a strong desire for sleep)
Yellow skin

What are the existing conditions these people have? *

Biliary Cirrhosis Primary (primary biliary cirrhosis (pbc) is a long-term liver disease that damages the small bile ducts in the liver. the build-up of bile damages the liver): 3 people, 9.68%

* Approximation only. Some reports may have incomplete information.

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