Betapace and Atorvastatin calcium drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Betapace (sotalol hydrochloride) and Atorvastatin calcium (atorvastatin calcium). Common drug interactions include arthralgia among females and asthenia among males.
The phase IV clinical study analyzes what interactions people have when they take Betapace and Atorvastatin calcium. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.
What is Betapace?
Betapace has active ingredients of sotalol hydrochloride. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 2,899 Betapace users. Check the latest studies of Betapace.
What is Atorvastatin calcium?
Atorvastatin calcium has active ingredients of atorvastatin calcium. It is often used in high blood cholesterol. eHealthMe is studying from 77,309 Atorvastatin calcium users. Check the latest studies of Atorvastatin calcium.
12 people who take Betapace and Atorvastatin calcium together, and have interactions are studied.

What are the common drug interactions of Betapace and Atorvastatin Calcium, by gender? *:
female:
- Arthralgia (joint pain)
- Back pain
- Cough
- Dysstasia (difficulty in standing)
- Ear haemorrhage (bleeding from ear)
- Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
- Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
- Myalgia (muscle pain)
- Skin discolouration (change of skin colour)
male:
- Asthenia (weakness)
- Amyotrophic lateral sclerosis (nervous system disease that attacks nerve cells called neurons in your brain and spinal cord)
- Cardiac failure congestive
- Cardioactive drug level above therapeutic
- Cardioactive drug level below therapeutic
- Chest discomfort
- Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
- Depression
- Diarrhoea
- Dizziness
What are the common drug interactions of Betapace and Atorvastatin Calcium, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Amyotrophic lateral sclerosis (nervous system disease that attacks nerve cells called neurons in your brain and spinal cord)
- Asthenia (weakness)
- Thrombosis (formation of a blood clot inside a blood vessel)
50-59:
- Abdominal distension
- Asthenia (weakness)
- Barrett's oesophagus (barrett's oesophagus is a disorder in which the lining of the oesophagus (the tube that carries food from the throat to the stomach) is damaged by stomach acid and changed to a lining similar to that of the stomach)
- Bundle branch block left (absence of transmission of electric impulses from the atrioventricular (av) bundle of his to the left ventricle)
- Cardiac failure congestive
- Cardioactive drug level above therapeutic
- Cardioactive drug level below therapeutic
- Chest discomfort
- Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
- Depression
60+:
- Anaemia (lack of blood)
- Fall
- Rib fracture
- Thrombocytopenia (decrease of platelets in blood)
- Fatigue (feeling of tiredness)
- Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
- Inappropriate antidiuretic hormone secretion
- Leukopenia (less number of white blood cells in blood)
- Nausea (feeling of having an urge to vomit)
- Neuropathy peripheral (surface nerve damage)
What are the existing conditions these people have? *
- Multiple Myeloma (cancer of the plasma cells): 5 people, 41.67%
- Pain: 2 people, 16.67%
- Type 2 Diabetes: 1 person, 8.33%
- Sleep Disorder: 1 person, 8.33%
- Neurotrophic Keratopathy (decreased corneal sensitivity and poor corneal healing): 1 person, 8.33%
- Musculoskeletal Pain (pain affects the bones, muscles, ligaments, tendons, and nerves): 1 person, 8.33%
- Metastasis (spreadable cancer to other organ from origin): 1 person, 8.33%
- Chest Pain: 1 person, 8.33%
- Arrhythmias (irregular heartbeat): 1 person, 8.33%
- Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 1 person, 8.33%
* Approximation only. Some reports may have incomplete information.
Do you take Betapace and Atorvastatin calcium?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Betapace (2,899 reports)
- Atorvastatin calcium (77,309 reports)
Browse all drug interactions of Betapace and Atorvastatin calcium:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Betapace:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Atorvastatin calcium:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Betapace and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Atorvastatin calcium and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Tesic D, Kostic M, Paunovic D, Jankovic SM, "Analysis of the cost–effectiveness of dronedarone versus amiodarone, propafenone, and sotalol in patients with atrial fibrillation: results for Serbia", Kardiologia Polska (Polish Heart Journal), 2016 Jan .
- Proti? D, Balti? S, Stupar N, Pavlov-Dolijanovi? S, Mugo?a S, Todorovi? Z, "A case of myositis with immunological background associated with statin use", Open Medicine, 2014 Oct .
- Goldie MP, "Atorvastatin: a new treatment for periodontal disease?", , 2012 Jan .
- Tesic D, Kostic M, Paunovic D, Jankovic SM, "Analysis of the cost–effectiveness of dronedarone versus amiodarone, propafenone, and sotalol in patients with atrial fibrillation: results for Serbia", Kardiologia Polska (Polish Heart Journal), 2016 Jan .
- Proti? D, Balti? S, Stupar N, Pavlov-Dolijanovi? S, Mugo?a S, Todorovi? Z, "A case of myositis with immunological background associated with statin use", Open Medicine, 2014 Oct .
- Goldie MP, "Atorvastatin: a new treatment for periodontal disease?", , 2012 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on sotalol hydrochloride and atorvastatin calcium (the active ingredients of Betapace and Atorvastatin calcium, respectively), and Betapace and Atorvastatin calcium (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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