Bicalutamide and Silodosin drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Bicalutamide (bicalutamide) and Silodosin (silodosin). Common drug interactions include death among males.
The phase IV clinical study analyzes what interactions people have when they take Bicalutamide and Silodosin. It is created by eHealthMe based on reports of 64 people who take the same drugs from the FDA, and is updated regularly.
What is Bicalutamide?
Bicalutamide has active ingredients of bicalutamide. It is often used in prostate cancer. eHealthMe is studying from 9,930 Bicalutamide users. Check the latest studies of Bicalutamide.
What is Silodosin?
Silodosin has active ingredients of silodosin. eHealthMe is studying from 3,839 Silodosin users. Check the latest studies of Silodosin.
64 people who take Bicalutamide and Silodosin together, and have interactions are studied.

What are the common drug interactions of Bicalutamide and Silodosin, by gender? *:
female:
n/a
male:
- Death
- Interstitial lung disease
- Hypertension (high blood pressure)
- Hypokalaemia (low potassium)
- Myalgia (muscle pain)
- Somnolence (a state of near-sleep, a strong desire for sleep)
- Basal cell carcinoma (a skin cancer, it rarely metastasizes or kills)
- Dermatitis acneiform (dermatoses including acne vulgaris, rosacea, folliculitis, and perioral dermatitis)
- Drug ineffective
- Loss of consciousness
What are the common drug interactions of Bicalutamide and Silodosin, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
n/a
60+:
- Death
- Pyrexia (fever)
- Cerebral infarction (less blood supply to brain resulting tissue damage)
- Dermatitis acneiform (dermatoses including acne vulgaris, rosacea, folliculitis, and perioral dermatitis)
- Drug ineffective
- Interstitial lung disease
- Loss of consciousness
- Ocular ischaemic syndrome (a disease of eye with weak blood supply affects the eye)
- Pain in extremity
- Ventricular tachycardia (rapid heartbeat that originates in one of the lower chambers (the ventricles) of the heart)
What are the existing conditions these people have? *
- High Blood Pressure: 20 people, 31.25%
- Enlarged Prostate: 13 people, 20.31%
- Pollakiuria (abnormally frequent passage of relatively small quantities or urine): 10 people, 15.62%
- Depression: 10 people, 15.62%
- Hypersensitivity: 8 people, 12.50%
- Hyperuricaemia (level of uric acid in the blood that is abnormally high): 7 people, 10.94%
- Heart Attack: 7 people, 10.94%
- Hyperlipidaemia (presence of excess lipids in the blood): 5 people, 7.81%
- Constipation: 5 people, 7.81%
- Back Pain: 5 people, 7.81%
* Approximation only. Some reports may have incomplete information.
Do you take Bicalutamide and Silodosin?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Bicalutamide (9,930 reports)
- Silodosin (3,839 reports)
Browse all drug interactions of Bicalutamide and Silodosin:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Bicalutamide:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Silodosin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Bicalutamide and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Silodosin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Peng, C. C., Chen, C. Y., Chen, C. R., Chen, C. J., Shen, K. H., Chen, K. C., & Peng, R. Y., "Renal Damaging Effect Elicited by Bicalutamide Therapy Uncovered Multiple Action Mechanisms As Evidenced by the Cell Model", Scientific reports, 2018 Jan .
- Peng, C. C., Chen, C. Y., Chen, C. R., Chen, C. J., Shen, K. H., Chen, K. C., & Peng, R. Y., "Renal Damaging Effect Elicited by Bicalutamide Therapy Uncovered Multiple Action Mechanisms As Evidenced by the Cell Model", Scientific reports, 2018 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on bicalutamide and silodosin (the active ingredients of Bicalutamide and Silodosin, respectively), and Bicalutamide and Silodosin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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