Bifido and Centrum silver drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Bifido (bifidobacteria) and Centrum silver (ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e). Common drug interactions include diabetic neuropathy among females and dizziness among males.

The phase IV clinical study analyzes what interactions people have when they take Bifido and Centrum silver. It is created by eHealthMe based on reports of 50 people who take the same drugs from the FDA, and is updated regularly.

What is Bifido?

Bifido has active ingredients of bifidobacteria. eHealthMe is studying from 5,030 Bifido users. Check the latest studies of Bifido.

What is Centrum silver?

Centrum silver has active ingredients of ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e. It is often used in vitamin supplementation. eHealthMe is studying from 19,997 Centrum silver users. Check the latest studies of Centrum silver.



On Jul, 09, 2026

50 people who take Bifido and Centrum silver together, and have interactions are studied.

Bifido and Centrum silver drug interactions.

What are the common drug interactions of Bifido and Centrum Silver, by gender? *:

female:

  1. Diabetic neuropathy (neuropathic disorders that are associated with diabetes mellitus)
  2. Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)
  3. Dizziness
  4. Dry eye (lack of adequate tears)
  5. Dysgeusia (disorder of the sense of taste)
  6. Dyspnoea (difficult or laboured respiration)
  7. Epistaxis (bleed from the nose)
  8. Eye irritation
  9. Gait disturbance
  10. Haemorrhage (bleeding)

male:

  1. Dizziness
  2. Constipation
  3. Joint abscess (pus in joints due to infection)
  4. Malaise (a feeling of general discomfort or uneasiness)
  5. Pneumonia
  6. Pruritus (severe itching of the skin)
  7. Rash
  8. Sepsis (a severe blood infection that can lead to organ failure and death)
  9. Thrombocytopenia (decrease of platelets in blood)
  10. Weight decreased

What are the common drug interactions of Bifido and Centrum Silver, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Pyrexia (fever)
  2. Rhinorrhoea (watery mucus discharge from the nose)
  3. Rotator cuff syndrome (a spectrum of conditions affecting the rotator cuff tendons of the shoulder)
  4. Weight decreased
  5. Dizziness
  6. Dyspnoea (difficult or laboured respiration)
  7. Hyperventilation
  8. Night sweats (sweating in night)
  9. Rash
  10. Arthralgia (joint pain)

60+:

  1. Asthenia (weakness)
  2. Pyrexia (fever)
  3. Muscular weakness (muscle weakness)
  4. Palpitations (feelings or sensations that your heart is pounding or racing)
  5. Pneumonia
  6. Rash
  7. Skin cancer
  8. Skin ulcer
  9. Constipation
  10. Diarrhoea

What are the existing conditions these people have? *

  1. Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 7 people, 14.00%
  2. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 6 people, 12.00%
  3. Pain: 4 people, 8.00%
  4. Multiple Myeloma (cancer of the plasma cells): 4 people, 8.00%
  5. Prostate Cancer: 3 people, 6.00%
  6. Immunodeficiency Common Variable: 3 people, 6.00%
  7. High Blood Pressure: 3 people, 6.00%
  8. High Blood Cholesterol: 3 people, 6.00%
  9. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 6.00%

* Approximation only. Some reports may have incomplete information.

Do you take Bifido and Centrum silver?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Bifido and Centrum silver:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Bifido:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Centrum silver:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Bifido and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Centrum silver and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on bifidobacteria and ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e (the active ingredients of Bifido and Centrum silver, respectively), and Bifido and Centrum silver (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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