Biktarvy and Cipro drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Biktarvy (bictegravir sodium; emtricitabine; tenofovir alafenamide fumarate) and Cipro (ciprofloxacin hydrochloride). Common drug interactions include anhedonia among females and anhedonia among males.

The phase IV clinical study analyzes what interactions people have when they take Biktarvy and Cipro. It is created by eHealthMe based on reports of 23 people who take the same drugs from the FDA, and is updated regularly.

What is Biktarvy?

Biktarvy has active ingredients of bictegravir sodium; emtricitabine; tenofovir alafenamide fumarate. It is often used in hiv infection. eHealthMe is studying from 19,543 Biktarvy users. Check the latest studies of Biktarvy.

What is Cipro?

Cipro has active ingredients of ciprofloxacin hydrochloride. It is often used in urinary tract infection. eHealthMe is studying from 35,126 Cipro users. Check the latest studies of Cipro.

On Jul, 11, 2026

23 people who take Biktarvy and Cipro together, and have interactions are studied.

What are the common drug interactions of Biktarvy and Cipro, by gender? *:

female:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Emotional distress
Osteoporosis (bones weak and more likely to break)
Pain
Bone density decreased
Depression
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Osteopenia (a condition where bone mineral density is lower than normal)
Pain in extremity

male:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Tibia fracture (fracture of lower leg bone)
Blood creatinine increased
Hypertension (high blood pressure)
Benign prostatic hyperplasia (benign enlargement of the prostate)
Fracture
Gout (uric acid crystals building up in the body)
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Arteriovenous fistula site complication

What are the common drug interactions of Biktarvy and Cipro, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Emotional distress
Pain
Chronic kidney disease
Osteoporosis (bones weak and more likely to break)
Bipolar disorder (mood disorder)
Bone density decreased
Hypertension (high blood pressure)
Multiple injuries

50-59:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Emotional distress
Pain
Bone density decreased
Osteoporosis (bones weak and more likely to break)
Renal impairment (severely reduced kidney function)
Blood creatinine increased
Benign prostatic hyperplasia (benign enlargement of the prostate)
Fracture

60+:

Chronic kidney disease
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Renal impairment (severely reduced kidney function)
Renal failure (kidney dysfunction)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Arteriovenous fistula site complication
Emotional distress
Gait disturbance
Injury

What are the existing conditions these people have? *

Pain: 3 people, 13.04%
Infection: 2 people, 8.70%
High Blood Pressure: 2 people, 8.70%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 8.70%
Dyspnea (difficult or laboured breathing): 2 people, 8.70%
Bronchitis Bacterial (inflammation of the mucous membrane in the bronchial tubes due to bacterial infection): 2 people, 8.70%

* Approximation only. Some reports may have incomplete information.

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