Biotin and Isosorbide dinitrate drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Biotin (biotin) and Isosorbide dinitrate (isosorbide dinitrate). Common drug interactions include fatigue among females and acute myocardial infarction among males.

The phase IV clinical study analyzes what interactions people have when they take Biotin and Isosorbide dinitrate. It is created by eHealthMe based on reports of 30 people who take the same drugs from the FDA, and is updated regularly.

What is Biotin?

Biotin has active ingredients of biotin. It is often used in hair loss. eHealthMe is studying from 35,393 Biotin users. Check the latest studies of Biotin.

What is Isosorbide dinitrate?

Isosorbide dinitrate has active ingredients of isosorbide dinitrate. It is often used in angina. eHealthMe is studying from 13,180 Isosorbide dinitrate users. Check the latest studies of Isosorbide dinitrate.



On Jul, 13, 2026

30 people who take Biotin and Isosorbide dinitrate together, and have interactions are studied.

Biotin and Isosorbide dinitrate drug interactions.

What are the common drug interactions of Biotin and Isosorbide Dinitrate, by gender? *:

female:

  1. Fatigue (feeling of tiredness)
  2. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  3. Hyperhidrosis (abnormally increased sweating)
  4. Vomiting
  5. Weight decreased
  6. Alanine aminotransferase increased
  7. Aspartate aminotransferase increased
  8. Blood cholesterol increased
  9. Balance disorder
  10. Chest pain

male:

  1. Acute myocardial infarction (acute heart attack)
  2. Cardiac arrest
  3. Cardiac failure
  4. Cardiogenic shock (inadequate circulation of blood)
  5. Ischaemic cardiomyopathy (weakness in the muscle of the heart due to inadequate oxygen delivery to the myocardium with coronary artery disease)
  6. Post procedural complication
  7. Ventricular arrhythmia (problem with the rate or rhythm of the heartbeat)

What are the common drug interactions of Biotin and Isosorbide Dinitrate, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
  2. Atrioventricular block (heart block)
  3. Death
  4. Headache (pain in head)
  5. Migraine (headache)
  6. Myalgia (muscle pain)
  7. Nausea (feeling of having an urge to vomit)

60+:

  1. Diarrhoea
  2. Abdominal pain upper
  3. Fall
  4. Balance disorder
  5. Contusion (a type of hematoma of tissue in which capillaries)
  6. Depression
  7. Drug ineffective
  8. Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters)
  9. Hallucination (an experience involving the perception of something not present)
  10. Hallucination, auditory (perceiving sounds without auditory stimulus)

What are the existing conditions these people have? *

  1. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 5 people, 16.67%
  2. High Blood Cholesterol: 4 people, 13.33%
  3. Hypersensitivity: 4 people, 13.33%
  4. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 10.00%
  5. Chest Pain: 3 people, 10.00%
  6. Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 3 people, 10.00%
  7. Coronary Heart Disease (narrowing or blockage of the coronary arteries): 3 people, 10.00%
  8. Stable Angina (a constant chest pain): 3 people, 10.00%
  9. High Blood Pressure: 3 people, 10.00%
  10. Angina Unstable (chest pain due to ischemia of the heart muscle- unstable): 3 people, 10.00%

* Approximation only. Some reports may have incomplete information.

Do you take Biotin and Isosorbide dinitrate?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Biotin and Isosorbide dinitrate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Biotin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Isosorbide dinitrate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Biotin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Isosorbide dinitrate and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on biotin and isosorbide dinitrate (the active ingredients of Biotin and Isosorbide dinitrate, respectively), and Biotin and Isosorbide dinitrate (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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