Bisoprolol fumarate and Aprepitant drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Bisoprolol fumarate (bisoprolol fumarate) and Aprepitant (aprepitant). Common drug interactions include ventricular dysfunction among females and cholangitis acute among males.

The phase IV clinical study analyzes what interactions people have when they take Bisoprolol fumarate and Aprepitant. It is created by eHealthMe based on reports of 89 people who take the same drugs from the FDA, and is updated regularly.

What is Bisoprolol fumarate?

Bisoprolol fumarate has active ingredients of bisoprolol fumarate. It is often used in high blood pressure. eHealthMe is studying from 40,828 Bisoprolol fumarate users. Check the latest studies of Bisoprolol fumarate.

What is Aprepitant?

Aprepitant has active ingredients of aprepitant. eHealthMe is studying from 6,992 Aprepitant users. Check the latest studies of Aprepitant.



On Jul, 10, 2026

89 people who take Bisoprolol fumarate and Aprepitant together, and have interactions are studied.

Bisoprolol fumarate and Aprepitant drug interactions.

What are the common drug interactions of Bisoprolol Fumarate and Aprepitant, by gender? *:

female:

  1. Ventricular dysfunction (heart dysfunction)
  2. Nausea (feeling of having an urge to vomit)
  3. White blood cell count decreased
  4. Thrombocytopenia (decrease of platelets in blood)
  5. Hemianopia (blindness or reduction in vision in one half of the visual field due to damage of the optic pathways in the brain)
  6. Skin fissures (a crack in the skin)
  7. Diarrhoea
  8. Interstitial lung disease
  9. Rash
  10. Somnolence (a state of near-sleep, a strong desire for sleep)

male:

  1. Cholangitis acute (rapid infection of bile duct)
  2. Cholangiocarcinoma (a cancer that forms glands or secretes significant amounts of mucins)
  3. Intestinal ischaemia (decreased supply of oxygenated blood to the intestines)
  4. Neutropenia (an abnormally low number of neutrophils)
  5. Splenic infarction (tissue damage of spleen)
  6. Klebsiella infection
  7. Oxygen saturation decreased
  8. Platelet count decreased
  9. Proteus infection (proteus can cause urinary tract infections)
  10. Respiratory distress (difficulty in breathing)

What are the common drug interactions of Bisoprolol Fumarate and Aprepitant, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. White blood cell count decreased
  2. Hemianopia (blindness or reduction in vision in one half of the visual field due to damage of the optic pathways in the brain)
  3. Nausea (feeling of having an urge to vomit)
  4. Skin fissures (a crack in the skin)
  5. Thrombocytopenia (decrease of platelets in blood)
  6. Diplopia (double vision)
  7. Mononeuropathy multiplex (a form of damage to one or more peripheral nerves -- the nerves outside the brain and spinal cord)

40-49:

  1. White blood cell count decreased
  2. Thrombocytopenia (decrease of platelets in blood)
  3. Hemianopia (blindness or reduction in vision in one half of the visual field due to damage of the optic pathways in the brain)
  4. Nausea (feeling of having an urge to vomit)
  5. Skin fissures (a crack in the skin)
  6. Influenza

50-59:

  1. Aplasia (defective development or congenital absence of an organ or tissue)
  2. Stomatitis (inflammation of mucous membrane of mouth)
  3. Myelosuppression (a decrease in the production of blood cells)
  4. Splenic infarction (tissue damage of spleen)
  5. Procedural pain
  6. Urinary tract infection

60+:

  1. Cholangitis acute (rapid infection of bile duct)
  2. Cholangiocarcinoma (a cancer that forms glands or secretes significant amounts of mucins)
  3. Neutropenia (an abnormally low number of neutrophils)
  4. Somnolence (a state of near-sleep, a strong desire for sleep)
  5. Klebsiella infection
  6. Left ventricular dysfunction
  7. Oxygen saturation decreased
  8. Platelet count decreased
  9. Polyneuropathy (neurological disorder that occurs when many peripheral nerves throughout the body malfunction simultaneously)
  10. Proteus infection (proteus can cause urinary tract infections)

What are the existing conditions these people have? *

  1. Nausea (feeling of having an urge to vomit): 16 people, 17.98%
  2. Diarrhea: 13 people, 14.61%
  3. Lung Cancer - Non-Small Cell (lung cancer): 13 people, 14.61%
  4. Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 12 people, 13.48%
  5. Lung Adenocarcinoma (a form of non-small cell lung cancer): 12 people, 13.48%
  6. Type 2 Diabetes: 9 people, 10.11%
  7. Breast Cancer Metastatic: 9 people, 10.11%
  8. Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 9 people, 10.11%
  9. Dyslipidaemia (abnormal amount of lipids): 8 people, 8.99%
  10. Headache (pain in head): 8 people, 8.99%

* Approximation only. Some reports may have incomplete information.

Do you take Bisoprolol fumarate and Aprepitant?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Bisoprolol fumarate and Aprepitant:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Bisoprolol fumarate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Aprepitant:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Bisoprolol fumarate and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Aprepitant and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on bisoprolol fumarate and aprepitant (the active ingredients of Bisoprolol fumarate and Aprepitant, respectively), and Bisoprolol fumarate and Aprepitant (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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