Boniva and Remeron drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Boniva (ibandronate sodium) and Remeron (mirtazapine). Common drug interactions include nausea among females and cardiac failure congestive among males.

The phase IV clinical study analyzes what interactions people have when they take Boniva and Remeron. It is created by eHealthMe based on reports of 55 people who take the same drugs from the FDA, and is updated regularly.

What is Boniva?

Boniva has active ingredients of ibandronate sodium. It is often used in osteoporosis. eHealthMe is studying from 27,340 Boniva users. Check the latest studies of Boniva.

What is Remeron?

Remeron has active ingredients of mirtazapine. It is often used in depression. eHealthMe is studying from 26,474 Remeron users. Check the latest studies of Remeron.



On Jul, 17, 2026

55 people who take Boniva and Remeron together, and have interactions are studied.

Boniva and Remeron drug interactions.

What are the common drug interactions of Boniva and Remeron, by gender? *:

female:

  1. Nausea (feeling of having an urge to vomit)
  2. Chronic left ventricular failure (long lasting functional impairment of left ventricle of heart)
  3. Dry eye (lack of adequate tears)
  4. Renal disorder (kidney disease)
  5. Diarrhoea
  6. Femur fracture
  7. Liver injury
  8. Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
  9. Spinal column stenosis (narrowing of spinal column)
  10. Weight decreased

male:

  1. Cardiac failure congestive
  2. Erythema (redness of the skin)
  3. Prostate cancer
  4. Pain in extremity
  5. Swelling
  6. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  7. Bone density decreased
  8. Emotional distress
  9. Fracture
  10. Gastrointestinal haemorrhage (bleeding gastrointestinal tract)

What are the common drug interactions of Boniva and Remeron, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Drug effect decreased
  2. Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)

50-59:

  1. Abdominal discomfort
  2. Cystitis (inflammation of the wall of the bladder)
  3. Dyspepsia (indigestion)
  4. Genital rash (rash on sex organ)
  5. Urinary tract infection
  6. Fall
  7. Head injury
  8. Inflammation
  9. Nasal disorder (diseases of nose)
  10. Skull fracture

60+:

  1. Dyspnoea (difficult or laboured respiration)
  2. Myelofibrosis (a disease in which abnormal blood cells and fibres build up inside the bone marrow)
  3. Coagulopathy (blood's ability to clot is impaired)
  4. Dry mouth
  5. Haematoma (collection of blood outside the blood vessels)
  6. Hyperhidrosis (abnormally increased sweating)
  7. Hypertension (high blood pressure)
  8. International normalised ratio increased
  9. Irritability
  10. Myelodysplastic syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged)

What are the existing conditions these people have? *

  1. Pain: 8 people, 14.55%
  2. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 5 people, 9.09%
  3. High Blood Pressure: 5 people, 9.09%
  4. Stress And Anxiety: 4 people, 7.27%
  5. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 4 people, 7.27%
  6. Ischaemic Stroke (stroke; caused by an interruption in the flow of blood to the brain): 4 people, 7.27%
  7. Osteopenia (a condition where bone mineral density is lower than normal): 3 people, 5.45%
  8. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 5.45%
  9. Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 3 people, 5.45%

* Approximation only. Some reports may have incomplete information.

Do you take Boniva and Remeron?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Boniva and Remeron:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Boniva:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Remeron:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Boniva and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Remeron and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on ibandronate sodium and mirtazapine (the active ingredients of Boniva and Remeron, respectively), and Boniva and Remeron (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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