Botox and Detrol drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Botox (botulinum toxin type a) and Detrol (tolterodine tartrate). Common drug interactions include peripheral ischaemia among females and body temperature increased among males.

The phase IV clinical study analyzes what interactions people have when they take Botox and Detrol. It is created by eHealthMe based on reports of 47 people who take the same drugs from the FDA, and is updated regularly.

What is Botox?

Botox has active ingredients of botulinum toxin type a. It is often used in migraine. eHealthMe is studying from 70,513 Botox users. Check the latest studies of Botox.

What is Detrol?

Detrol has active ingredients of tolterodine tartrate. It is often used in urge incontinence. eHealthMe is studying from 28,669 Detrol users. Check the latest studies of Detrol.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

47 people who take Botox and Detrol together, and have interactions are studied.

What are the common drug interactions of Botox and Detrol, by gender? *:

female:

Peripheral ischaemia (impaired circulation to an extremity)
Rectal prolapse (falling of rectum from normal place)
Sinusitis (inflammation of sinus)
Swelling
Swelling face
Tooth extraction
Uterovaginal prolapse
Wound decomposition
Wound secretion
Basal cell carcinoma (a skin cancer, it rarely metastasizes or kills)

male:

Body temperature increased
Drug ineffective
Burning sensation
Crying
Dehydration (dryness resulting from the removal of water)
Depression
Dysuria (painful or difficult urination)
Fall
Fatigue (feeling of tiredness)
Insomnia (sleeplessness)

What are the common drug interactions of Botox and Detrol, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Anxiety
Aphthous ulcer (mouth ulcer)
Asthenia (weakness)
Back pain
Bacterial test positive
Balance disorder
Body temperature increased
Burning sensation
Crying
Dehydration (dryness resulting from the removal of water)

30-39:

Body temperature increased
Drug intolerance (drug sensitivity)
Feeling of body temperature change
Nausea (feeling of having an urge to vomit)

40-49:

Movement disorder (neurological syndromes where they may be excess of movement or a paucity of movement that is not connected to weakness)
Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
Paraesthesia oral (sensation of tingling, tickling, prickling, pricking, or burning of a person's oral with no apparent long-term physical effect)
Rash
Rash pruritic (redness with itching)
Road traffic accident
Urticaria (rash of round, red welts on the skin that itch intensely)
White blood cell count increased
Arthralgia (joint pain)
Back pain

50-59:

Injection site pain
Fall
Loss of consciousness
Respiratory fume inhalation disorder (the problem of respiratory irritants and inhaled toxic)

60+:

Fall
Headache (pain in head)
Bladder prolapse (bulging of one or more of the pelvic organs into the vagina)
Bone disorder
Bone fistula
Cardiac failure congestive
Carotid artery stenosis (narrowing of carotid artery)
Cellulitis (infection under the skin)
Cerebral atrophy (decrement in size of brain)
Chronic inflammatory demyelinating polyradiculoneuropathy (long lasting infection of nerves outside brain and spinal cord)

What are the existing conditions these people have? *

Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 13 people, 27.66%
Pain: 12 people, 25.53%
Sleep Disorder: 10 people, 21.28%
Muscle Spasms (muscle contraction): 9 people, 19.15%
Muscle Spasticity (tight or stiff muscles and an inability to control those muscles): 8 people, 17.02%
Neuralgia (pain in one or more nerves): 7 people, 14.89%
Urinary Tract Infection: 6 people, 12.77%
Urinary Tract Infection Bacterial: 5 people, 10.64%
Fatigue (feeling of tiredness): 5 people, 10.64%
Gait Disturbance: 5 people, 10.64%

* Approximation only. Some reports may have incomplete information.

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