Nuedexta and Memantine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Nuedexta (dextromethorphan hydrobromide; quinidine sulfate) and Memantine (memantine). Common drug interactions include drug ineffective among females and confusional state among males.

The phase IV clinical study analyzes what interactions people have when they take Nuedexta and Memantine. It is created by eHealthMe based on reports of 41 people who take the same drugs from the FDA, and is updated regularly.

What is Nuedexta?

Nuedexta has active ingredients of dextromethorphan hydrobromide; quinidine sulfate. eHealthMe is studying from 3,781 Nuedexta users. Check the latest studies of Nuedexta.

What is Memantine?

Memantine has active ingredients of memantine. It is often used in alzheimer's disease. eHealthMe is studying from 10,266 Memantine users. Check the latest studies of Memantine.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

41 people who take Nuedexta and Memantine together, and have interactions are studied.

Nuedexta and Memantine drug interactions.

What are the common drug interactions of Nuedexta and Memantine, by gender? *:

female:

Drug ineffective
Urinary tract infection
Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
Tremor (trembling or shaking movements in one or more parts of your body)
Breast mass
Fatigue (feeling of tiredness)
Immunosuppression
Nausea (feeling of having an urge to vomit)
Pneumonia
Pulmonary haemorrhage (acute bleeding from the lung)

male:

Confusional state
Dizziness
Speech disorder
Agitation (state of anxiety or nervous excitement)
Anger
Asthenia (weakness)
Bacterial test positive
Dementia alzheimer's type (loss of mental ability with alzheimer's symptom)
Depression
Disease recurrence

What are the common drug interactions of Nuedexta and Memantine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Affect lability (emotional incontinence)
Affective disorder (mental disorder)
Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
Dizziness
Fatigue (feeling of tiredness)
Irritability
Malaise (a feeling of general discomfort or uneasiness)
Micturition urgency (urgency to pass the urine)
Multiple sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)

40-49:

Fatigue (feeling of tiredness)
Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
Stress

50-59:

Breast mass
Drug ineffective
Nausea (feeling of having an urge to vomit)
Urinary tract infection
Anxiety
Arthralgia (joint pain)
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Arthropathy
Asthenia (weakness)
Balance disorder

60+:

Death
Immunosuppression
Urosepsis (secondary infection that occurs when a urinary tract infection spreads to the bloodstream)
Insomnia (sleeplessness)
Micturition urgency (urgency to pass the urine)
Pollakiuria (abnormally frequent passage of relatively small quantities or urine)
Speech disorder
Weight decreased
Aggression
Anger

What are the existing conditions these people have? *

Affect Lability (emotional incontinence): 9 people, 21.95%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 8 people, 19.51%
Parkinson's Disease: 7 people, 17.07%
Depression: 6 people, 14.63%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 14.63%
Stress And Anxiety: 6 people, 14.63%
Muscle Spasms (muscle contraction): 5 people, 12.20%
Dementia (madness): 5 people, 12.20%
High Blood Pressure: 5 people, 12.20%
Migraine (headache): 5 people, 12.20%

* Approximation only. Some reports may have incomplete information.

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