Botox and Revatio drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Botox (botulinum toxin type a) and Revatio (sildenafil citrate). Common drug interactions include diarrhoea among females and surgery among males.

The phase IV clinical study analyzes what interactions people have when they take Botox and Revatio. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.

What is Botox?

Botox has active ingredients of botulinum toxin type a. It is often used in migraine. eHealthMe is studying from 70,513 Botox users. Check the latest studies of Botox.

What is Revatio?

Revatio has active ingredients of sildenafil citrate. It is often used in pulmonary hypertension. eHealthMe is studying from 44,849 Revatio users. Check the latest studies of Revatio.

On Jul, 06, 2026

16 people who take Botox and Revatio together, and have interactions are studied.

What are the common drug interactions of Botox and Revatio, by gender? *:

female:

Diarrhoea
Malaise (a feeling of general discomfort or uneasiness)
Nausea (feeling of having an urge to vomit)
Pallor
Palpitations (feelings or sensations that your heart is pounding or racing)
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
Cardiac disorder
Chest discomfort
Chest pain
Drug rash with eosinophilia and systemic symptoms (adverse drug reactions with rash)

male:

Surgery

What are the common drug interactions of Botox and Revatio, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
Chest discomfort
Chest pain
Drug rash with eosinophilia and systemic symptoms (adverse drug reactions with rash)
Histiocytosis haematophagic
Malaise (a feeling of general discomfort or uneasiness)
Nausea (feeling of having an urge to vomit)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Pericarditis (inflammation of the pericardium)
Rash pruritic (redness with itching)

30-39:

n/a

40-49:

Thyroid disorder (thyroid diseases)
Pallor
Palpitations (feelings or sensations that your heart is pounding or racing)
Diarrhoea
Flushing (the warm, red condition of human skin)
Anxiety
Dyspnoea exertional (breathlessness or shortness of breath)
Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Syncope (loss of consciousness with an inability to maintain postural tone)

50-59:

n/a

60+:

Infection
Malaise (a feeling of general discomfort or uneasiness)
Unresponsive to stimuli
White blood cell count increased

What are the existing conditions these people have? *

Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 12 people, 75.00%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 2 people, 12.50%
Osteitis (a general term for inflammation of bone): 1 person, 6.25%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 1 person, 6.25%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

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