Botox and Rytary drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Botox (botulinum toxin type a) and Rytary (carbidopa; levodopa). Common drug interactions include parkinson's disease among females and fall among males.

The phase IV clinical study analyzes what interactions people have when they take Botox and Rytary. It is created by eHealthMe based on reports of 60 people who take the same drugs from the FDA, and is updated regularly.

What is Botox?

Botox has active ingredients of botulinum toxin type a. It is often used in migraine. eHealthMe is studying from 70,513 Botox users. Check the latest studies of Botox.

What is Rytary?

Rytary has active ingredients of carbidopa; levodopa. eHealthMe is studying from 17,270 Rytary users. Check the latest studies of Rytary.



On Jul, 06, 2026

60 people who take Botox and Rytary together, and have interactions are studied.

Botox and Rytary drug interactions.

What are the common drug interactions of Botox and Rytary, by gender? *:

female:

  1. Parkinson's disease
  2. Seizure (abnormal excessive or synchronous neuronal activity in the brain)
  3. Seizure like phenomena (a variety of medical conditions may produce sudden episodes which have some similarities to epileptic seizures)
  4. Tachycardia (a heart rate that exceeds the range of 100 beats/min)
  5. Therapeutic response unexpected
  6. Torticollis (a twisted neck in which the head is tipped to one side, while the chin is turned to the other)
  7. Vomiting
  8. Weight increased
  9. Hallucination (an experience involving the perception of something not present)
  10. Fall

male:

  1. Fall
  2. Hypertension (high blood pressure)
  3. Parkinson's disease
  4. Abnormal dreams
  5. Anxiety
  6. Arrhythmia (irregular heartbeat)
  7. Dementia (madness)
  8. Disorientation (disability in which the senses of time, direction, and recognition of people and places)
  9. Dysarthria (speech disorder)
  10. Hallucination (an experience involving the perception of something not present)

What are the common drug interactions of Botox and Rytary, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Bladder cancer
  2. Confusional state
  3. Drug ineffective
  4. Dysphagia (a condition in which swallowing is difficult or painful)
  5. Fall
  6. Gait disturbance
  7. Hallucination (an experience involving the perception of something not present)
  8. Initial insomnia (feeling of inadequate or poor-quality sleep)
  9. Nonspecific reaction (unspecified reaction)
  10. Panic attack

60+:

  1. Fall
  2. Somnolence (a state of near-sleep, a strong desire for sleep)
  3. Adverse event
  4. Abnormal behaviour
  5. Confusional state
  6. Dementia (madness)
  7. Hypertension (high blood pressure)
  8. Abnormal dreams
  9. Arrhythmia (irregular heartbeat)
  10. Death

What are the existing conditions these people have? *

  1. Parkinson's Disease: 46 people, 76.67%
  2. Hallucinations (sensations that appear real but are created by your mind): 8 people, 13.33%
  3. Delusion (a false belief or opinion): 8 people, 13.33%
  4. Drooling (drop saliva uncontrollably from the mouth): 7 people, 11.67%
  5. Stress And Anxiety: 5 people, 8.33%
  6. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 8.33%
  7. Dyskinesia (abnormality or impairment of voluntary movement): 5 people, 8.33%
  8. Movement - Uncontrolled Or Slow: 4 people, 6.67%
  9. Torticollis (a twisted neck in which the head is tipped to one side, while the chin is turned to the other): 3 people, 5.00%
  10. Seasonal Allergy (allergic condition due to certain season): 3 people, 5.00%

* Approximation only. Some reports may have incomplete information.

Do you take Botox and Rytary?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Botox and Rytary:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Botox:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Rytary:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Botox and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Rytary and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on botulinum toxin type a and carbidopa; levodopa (the active ingredients of Botox and Rytary, respectively), and Botox and Rytary (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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