Botox and Zometa drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Botox (botulinum toxin type a) and Zometa (zoledronic acid). Common drug interactions include mass among females and acne among males.

The phase IV clinical study analyzes what interactions people have when they take Botox and Zometa. It is created by eHealthMe based on reports of 35 people who take the same drugs from the FDA, and is updated regularly.

What is Botox?

Botox has active ingredients of botulinum toxin type a. It is often used in migraine. eHealthMe is studying from 70,513 Botox users. Check the latest studies of Botox.

What is Zometa?

Zometa has active ingredients of zoledronic acid. It is often used in multiple myeloma. eHealthMe is studying from 71,434 Zometa users. Check the latest studies of Zometa.

On Jul, 19, 2026

35 people who take Botox and Zometa together, and have interactions are studied.

What are the common drug interactions of Botox and Zometa, by gender? *:

female:

Mass
Tooth extraction
Swelling
Swelling face
Neuropathy peripheral (surface nerve damage)
Anxiety
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Chronic sinusitis (long lasting inflammation of the paranasal sinuses)
Deformity (disfigurement)
Dental caries

male:

Acne (skin problems that cause pimples)
Eye swelling
Pruritus (severe itching of the skin)
Rash macular (small, flat red spots)

What are the common drug interactions of Botox and Zometa, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Deformity (disfigurement)
Dental caries
Depression
Dysgeusia (disorder of the sense of taste)
Emotional distress
Erythema (redness of the skin)
Hypoaesthesia oral (reduced sense of touch or sensation in mouth)
Mass
Metastases to bone (cancer spreads to bone)
Metastases to liver (cancer spreads to liver)

50-59:

Anaemia (lack of blood)
Eye pruritus (eye itching)
Lacrimation increased
Neuropathy peripheral (surface nerve damage)
Vision blurred
Anxiety
Death
Dysphagia (a condition in which swallowing is difficult or painful)
Hypersensitivity
Lymphadenopathy (disease or enlargement of lymph nodes)

60+:

Anaemia (lack of blood)
Arteriosclerosis (thickening and hardening of arteries)
General physical condition
Haematoma (collection of blood outside the blood vessels)
Hypertonic bladder (bladder-storage function that causes a sudden urge to urinate)
Impaired healing
Infection
Intermittent claudication
Meningioma (a diverse set of tumours arising from the meninges)
Metastases to bone (cancer spreads to bone)

What are the existing conditions these people have? *

Neoplasm Malignant (cancer tumour): 18 people, 51.43%
Pain: 13 people, 37.14%
Depression: 13 people, 37.14%
Pain In Jaw: 12 people, 34.29%
Stress And Anxiety: 2 people, 5.71%
Immunodeficiency Common Variable: 2 people, 5.71%

* Approximation only. Some reports may have incomplete information.

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