Bricanyl and Actrapid drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Bricanyl (terbutaline sulfate) and Actrapid (insulin). Common drug interactions include toxic epidermal necrolysis among females and bronchitis among males.
The phase IV clinical study analyzes what interactions people have when they take Bricanyl and Actrapid. It is created by eHealthMe based on reports of 46 people who take the same drugs from the FDA, and is updated regularly.
What is Bricanyl?
Bricanyl has active ingredients of terbutaline sulfate. It is often used in asthma. eHealthMe is studying from 6,020 Bricanyl users. Check the latest studies of Bricanyl.
What is Actrapid?
Actrapid has active ingredients of insulin. eHealthMe is studying from 4,864 Actrapid users. Check the latest studies of Actrapid.
46 people who take Bricanyl and Actrapid together, and have interactions are studied.

What are the common drug interactions of Bricanyl and Actrapid, by gender? *:
female:
- Toxic epidermal necrolysis (a rare, life-threatening skin condition that is usually caused by a reaction to drugs causes wide spread skin destruction)
- Stevens-johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)
- Sepsis (a severe blood infection that can lead to organ failure and death)
- Septic shock (shock due to blood infection)
- Anxiety
- Depression
- Pneumonia staphylococcal (pneumonia staphylococcal infections are usually caused by the organism staphylococcus aureus)
- Pneumonia
- Acidosis (build-up of carbon dioxide in the blood)
- Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
male:
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
- Abdominal pain
- Renal failure (kidney dysfunction)
- Sudden death
- Agitation (state of anxiety or nervous excitement)
- Anaemia (lack of blood)
- Anaphylactic shock (severe and rapid and sometimes fatal hypersensitivity reaction to a substance)
- Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
- Disease progression
- Dysuria (painful or difficult urination)
What are the common drug interactions of Bricanyl and Actrapid, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Septic shock (shock due to blood infection)
- Toxic epidermal necrolysis (a rare, life-threatening skin condition that is usually caused by a reaction to drugs causes wide spread skin destruction)
- Anxiety
- Depression
- Pneumonia staphylococcal (pneumonia staphylococcal infections are usually caused by the organism staphylococcus aureus)
- Pneumonia
30-39:
- Stevens-johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)
- Sepsis (a severe blood infection that can lead to organ failure and death)
- Toxic epidermal necrolysis (a rare, life-threatening skin condition that is usually caused by a reaction to drugs causes wide spread skin destruction)
40-49:
- Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
- Pneumonia
- Pneumonia haemophilus (haemophilus influenzae type b (hib) bacteria include pneumonia)
- Blood glucose increased
50-59:
- Anxiety
- Depression
- Pneumonia staphylococcal (pneumonia staphylococcal infections are usually caused by the organism staphylococcus aureus)
- Septic shock (shock due to blood infection)
- Toxic epidermal necrolysis (a rare, life-threatening skin condition that is usually caused by a reaction to drugs causes wide spread skin destruction)
- Pneumonia
- Rash
- Sinusitis (inflammation of sinus)
60+:
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
- Abdominal pain
- Gastrointestinal infection (infection of stomach and intestine)
- Hyperkalaemia (damage to or disease of the kidney)
- Nausea (feeling of having an urge to vomit)
- Acute pulmonary oedema (sudden deposit of fluid in the lung))
- Renal failure (kidney dysfunction)
- Sudden death
- Agitation (state of anxiety or nervous excitement)
- Anaemia (lack of blood)
What are the existing conditions these people have? *
- Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 22 people, 47.83%
- Agitation (state of anxiety or nervous excitement): 21 people, 45.65%
- Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi): 15 people, 32.61%
- Infection: 15 people, 32.61%
- Metabolic Disorder (an abnormal function and pattern of body fat. insulin resistance refers to the diminished ability of cells to respond to the action of insulin in promoting the transport of the sugar glucose, from blood into muscles and other tissues): 14 people, 30.43%
- Cardiac Failure: 14 people, 30.43%
- Constipation: 14 people, 30.43%
- Extrapyramidal Disorder (involuntary muscle spasms in the face and neck): 14 people, 30.43%
- Flatulence (flatus expelled through the anus): 14 people, 30.43%
- Gallstones (stone formation by bile component): 14 people, 30.43%
* Approximation only. Some reports may have incomplete information.
Do you take Bricanyl and Actrapid?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Bricanyl and Actrapid:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Bricanyl:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Actrapid:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Bricanyl and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Actrapid and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on terbutaline sulfate and insulin (the active ingredients of Bricanyl and Actrapid, respectively), and Bricanyl and Actrapid (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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