Hydrocortisone and Valcyte drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Hydrocortisone (hydrocortisone) and Valcyte (valganciclovir hydrochloride). Common drug interactions include oedema peripheral among females and sepsis among males.

The phase IV clinical study analyzes what interactions people have when they take Hydrocortisone and Valcyte. It is created by eHealthMe based on reports of 41 people who take the same drugs from the FDA, and is updated regularly.

What is Hydrocortisone?

Hydrocortisone has active ingredients of hydrocortisone. It is often used in addison's disease. eHealthMe is studying from 40,425 Hydrocortisone users. Check the latest studies of Hydrocortisone.

What is Valcyte?

Valcyte has active ingredients of valganciclovir hydrochloride. It is often used in cmv - immunocompromised host. eHealthMe is studying from 6,409 Valcyte users. Check the latest studies of Valcyte.



On Jul, 26, 2026

41 people who take Hydrocortisone and Valcyte together, and have interactions are studied.

Hydrocortisone and Valcyte drug interactions.

What are the common drug interactions of Hydrocortisone and Valcyte, by gender? *:

female:

  1. Oedema peripheral (superficial swelling)
  2. Pneumonia
  3. Pyelonephritis (inflammation of kidney caused by bacteria)
  4. Pyrexia (fever)
  5. Squamous cell carcinoma (a cancer of a kind of epithelial cell)
  6. Urosepsis (secondary infection that occurs when a urinary tract infection spreads to the bloodstream)
  7. Abdominal hernia
  8. Abdominal pain
  9. Agitation (state of anxiety or nervous excitement)
  10. Anaemia (lack of blood)

male:

  1. Sepsis (a severe blood infection that can lead to organ failure and death)
  2. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
  3. Dementia (madness)
  4. General physical health deterioration (weak health status)
  5. Hypertension (high blood pressure)
  6. Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
  7. Loss of consciousness
  8. Malnutrition (a condition that results from eating a diet in which certain nutrients are lacking)
  9. Nausea (feeling of having an urge to vomit)
  10. Pneumonia

What are the common drug interactions of Hydrocortisone and Valcyte, by age (0-1 to 60+)? *:

0-1:

  1. Death
  2. Hospitalisation
  3. Pyrexia (fever)
  4. Vomiting

2-9:

n/a

10-19:

  1. Renal failure acute (rapid kidney dysfunction)

20-29:

  1. Body temperature increased
  2. Malaise (a feeling of general discomfort or uneasiness)
  3. Renal failure acute (rapid kidney dysfunction)

30-39:

  1. Arthralgia (joint pain)
  2. Joint swelling
  3. Oedema peripheral (superficial swelling)
  4. Pain in extremity
  5. Serum sickness (hypersensitivity reaction that results from the injection of heterologous or foreign protein or serum)

40-49:

  1. Arthralgia (joint pain)
  2. Asthenia (weakness)
  3. Brain oedema (excess accumulation of fluid in the intracellular or extracellular spaces of the brain)
  4. Chorea (abnormal involuntary movement disorder)
  5. Coma (state of unconsciousness lasting more than six hours)
  6. Deformity (disfigurement)
  7. Diabetes insipidus (diabetes caused by a deficiency of the pituitary hormone vasopressin, which regulates kidney function)
  8. Erythema (redness of the skin)
  9. Exfoliative rash (scaly red generalized skin rash)
  10. Fanconi syndrome acquired (self developed genetic disease of kidney damage due to defective transport system)

50-59:

  1. Heart transplant rejection
  2. Hypoparathyroidism secondary (inadequate secretion of parathyroid hormone resulting in abnormally low levels of calcium in the blood -due to another disease)
  3. Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
  4. Mycobacterium avium complex infection
  5. Neck pain
  6. Pyrexia (fever)
  7. Renal failure (kidney dysfunction)
  8. Renal failure chronic (long lasting kidney dysfunction)
  9. Renal mass (mass in kidney)
  10. Seroma (a tumour like collection of serum in the tissues)

60+:

  1. Hypertension (high blood pressure)
  2. Hypotension (abnormally low blood pressure)
  3. Loss of consciousness
  4. Malnutrition (a condition that results from eating a diet in which certain nutrients are lacking)
  5. Nausea (feeling of having an urge to vomit)
  6. Renal failure acute (rapid kidney dysfunction)
  7. Respiratory failure (inadequate gas exchange by the respiratory system)
  8. Sepsis (a severe blood infection that can lead to organ failure and death)
  9. Shock (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin)
  10. Subdural haematoma (blood collects between the skull and the surface of the brain)

What are the existing conditions these people have? *

  1. Immunodeficiency Disorders: 4 people, 9.76%
  2. High Blood Pressure: 4 people, 9.76%
  3. Cytomegalovirus Infection: 4 people, 9.76%
  4. Gastric Disorder (disease of stomach): 3 people, 7.32%
  5. Cough: 3 people, 7.32%

* Approximation only. Some reports may have incomplete information.

Do you take Hydrocortisone and Valcyte?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Hydrocortisone and Valcyte:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Hydrocortisone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Valcyte:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Hydrocortisone and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Valcyte and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on hydrocortisone and valganciclovir hydrochloride (the active ingredients of Hydrocortisone and Valcyte, respectively), and Hydrocortisone and Valcyte (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: