Brilinta and Clexane drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Brilinta (ticagrelor) and Clexane (enoxaparin sodium). Common drug interactions include catheter site haematoma among females and brain death among males.
The phase IV clinical study analyzes what interactions people have when they take Brilinta and Clexane. It is created by eHealthMe based on reports of 37 people who take the same drugs from the FDA, and is updated regularly.
What is Brilinta?
Brilinta has active ingredients of ticagrelor. It is often used in stent. eHealthMe is studying from 22,469 Brilinta users. Check the latest studies of Brilinta.
What is Clexane?
Clexane has active ingredients of enoxaparin sodium. eHealthMe is studying from 14,679 Clexane users. Check the latest studies of Clexane.
37 people who take Brilinta and Clexane together, and have interactions are studied.

What are the common drug interactions of Brilinta and Clexane, by gender? *:
female:
- Catheter site haematoma (blood clot at catheter site)
- Haematoma (collection of blood outside the blood vessels)
- Gastric haemorrhage (bleeding stomach)
- Gastric ulcer (stomach ulcer)
- Upper gastrointestinal haemorrhage (upper gastrointestinal bleeding)
- Cardiogenic shock (inadequate circulation of blood)
- Acute myocardial infarction (acute heart attack)
- Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
- Arterial occlusive disease (slow process through which arteries throughout the body become progressively narrowed and eventually completely blocked)
- Brain herniation (brain herniation is a potentially deadly side effect of very high intracranial pressure that occurs when a part of the brain is squeezed across structures within the skull)
male:
- Brain death
- Acute myocardial infarction (acute heart attack)
- Gastric haemorrhage (bleeding stomach)
- Gout (uric acid crystals building up in the body)
- Haemoglobin decreased
- Myalgia (muscle pain)
- Pulmonary oedema (fluid accumulation in the lungs)
- Rectal haemorrhage (bleeding from anus)
- Activities of daily living impaired
- Angina pectoris (chest pain due to ischemia of the heart muscle)
What are the common drug interactions of Brilinta and Clexane, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Alanine aminotransferase increased
- Thermal burn (burn by heat)
40-49:
n/a
50-59:
- Brain death
- Carotid artery occlusion (artery blockage)
- Cerebellar haemorrhage (bleeding in cerebeller)
- Cardiogenic shock (inadequate circulation of blood)
- Activities of daily living impaired
- Acute myocardial infarction (acute heart attack)
- Angina pectoris (chest pain due to ischemia of the heart muscle)
- Cardiac failure acute
- Coronary artery restenosis (recurrence of narrowing of artery)
- Dizziness
60+:
- Gastric haemorrhage (bleeding stomach)
- Acute myocardial infarction (acute heart attack)
- Cardiogenic shock (inadequate circulation of blood)
- Cerebral haemorrhage (bleeding within the brain)
- Gout (uric acid crystals building up in the body)
- Haemoglobin decreased
- Myalgia (muscle pain)
- Rectal haemorrhage (bleeding from anus)
- Brain compression
- Coma (state of unconsciousness lasting more than six hours)
What are the existing conditions these people have? *
- Acute Coronary Syndrome (acute chest pain and other symptoms that happen because the heart does not get blood): 14 people, 37.84%
- Heart Attack: 8 people, 21.62%
- Acute Myocardial Infarction (acute heart attack): 7 people, 18.92%
- Coronary Heart Disease (narrowing or blockage of the coronary arteries): 2 people, 5.41%
* Approximation only. Some reports may have incomplete information.
Do you take Brilinta and Clexane?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Brilinta and Clexane:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Brilinta:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Clexane:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Brilinta and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Clexane and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on ticagrelor and enoxaparin sodium (the active ingredients of Brilinta and Clexane, respectively), and Brilinta and Clexane (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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