Morphine and Lumakras drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Morphine (morphine sulfate) and Lumakras (sotorasib). Common drug interactions include hypokalaemia among females and cardiac failure among males.

The phase IV clinical study analyzes what interactions people have when they take Morphine and Lumakras. It is created by eHealthMe based on reports of 33 people who take the same drugs from the FDA, and is updated regularly.

What is Morphine?

Morphine has active ingredients of morphine sulfate. It is often used in pain. eHealthMe is studying from 182,913 Morphine users. Check the latest studies of Morphine.

What is Lumakras?

Lumakras has active ingredients of sotorasib. eHealthMe is studying from 1,895 Lumakras users. Check the latest studies of Lumakras.

On Jul, 14, 2026

33 people who take Morphine and Lumakras together, and have interactions are studied.

Morphine and Lumakras drug interactions.

What are the common drug interactions of Morphine and Lumakras, by gender? *:

female:

Hypokalaemia (low potassium)
Diarrhoea
Constipation
Cholestasis (a condition where bile cannot flow from the liver to the duodenum)
Hypocalcaemia (levels of calcium in blood serum are abnormally low)
Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
Asthenia (weakness)
Liver disorder (liver diseases)
Vomiting
Arthritis (form of joint disorder that involves inflammation of one or more joints)

male:

Cardiac failure
Fatigue (feeling of tiredness)
Dry mouth
Dyspnoea (difficult or laboured respiration)
Gait disturbance
Oedema peripheral (superficial swelling)
Productive cough
Somnolence (a state of near-sleep, a strong desire for sleep)
Chest pain
Disease progression

What are the common drug interactions of Morphine and Lumakras, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Cholestasis (a condition where bile cannot flow from the liver to the duodenum)
Drug intolerance (drug sensitivity)
Arthralgia (joint pain)
Bone pain
Oedema peripheral (superficial swelling)
Productive cough
Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
Chest pain
Constipation
Pulmonary embolism (blockage of the main artery of the lung)

60+:

Hypokalaemia (low potassium)
Constipation
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Liver disorder (liver diseases)
Metastatic bronchial carcinoma (spread of cancer to bronchi tumour)
Productive cough
Rhinorrhoea (watery mucus discharge from the nose)
Alanine aminotransferase increased
Aspartate aminotransferase increased
Dyspnoea (difficult or laboured respiration)

What are the existing conditions these people have? *

Lung Neoplasm Malignant (cancer tumour of lung): 12 people, 36.36%
K-Ras Gene Mutation: 11 people, 33.33%
Lung Adenocarcinoma (a form of non-small cell lung cancer): 6 people, 18.18%
High Blood Pressure: 4 people, 12.12%
Lung Cancer - Non-Small Cell (lung cancer): 4 people, 12.12%
Diarrhea: 4 people, 12.12%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 3 people, 9.09%
Gastric Disorder (disease of stomach): 2 people, 6.06%
Cardiac Failure: 2 people, 6.06%
Diabetes: 2 people, 6.06%

* Approximation only. Some reports may have incomplete information.

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