Brilinta and Compazine drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Brilinta (ticagrelor) and Compazine (prochlorperazine maleate). Common drug interactions include angina pectoris among females and hypertransaminasaemia among males.
The phase IV clinical study analyzes what interactions people have when they take Brilinta and Compazine. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.
What is Brilinta?
Brilinta has active ingredients of ticagrelor. It is often used in stent. eHealthMe is studying from 22,469 Brilinta users. Check the latest studies of Brilinta.
What is Compazine?
Compazine has active ingredients of prochlorperazine maleate. It is often used in indigestion. eHealthMe is studying from 13,646 Compazine users. Check the latest studies of Compazine.
18 people who take Brilinta and Compazine together, and have interactions are studied.

What are the common drug interactions of Brilinta and Compazine, by gender? *:
female:
- Angina pectoris (chest pain due to ischemia of the heart muscle)
- Abdominal discomfort
- Arthropathy
- Back pain
- Bone disorder
- Drug intolerance (drug sensitivity)
- Fatigue (feeling of tiredness)
- Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
- Hypoaesthesia (reduced sense of touch or sensation)
- Lymphadenopathy (disease or enlargement of lymph nodes)
male:
- Hypertransaminasaemia
- Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
- Myalgia (muscle pain)
- Procedural pain
- Pyrexia (fever)
- Sepsis (a severe blood infection that can lead to organ failure and death)
- Urinary tract infection
- Urosepsis (secondary infection that occurs when a urinary tract infection spreads to the bloodstream)
- Urticaria (rash of round, red welts on the skin that itch intensely)
- Arrhythmia (irregular heartbeat)
What are the common drug interactions of Brilinta and Compazine, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Abdominal discomfort
- Arthropathy
- Bone disorder
- Fatigue (feeling of tiredness)
- Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
50-59:
n/a
60+:
- Hypertransaminasaemia
- Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
- Drug intolerance (drug sensitivity)
- Escherichia bacteraemia (presence of bacteria escherichia coli in the blood)
- Escherichia infection (bacterial infection by escherichia coli)
- Hypoaesthesia (reduced sense of touch or sensation)
- Lymphadenopathy (disease or enlargement of lymph nodes)
- Myalgia (muscle pain)
- Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
- Procedural pain
What are the existing conditions these people have? *
- Multiple Myeloma (cancer of the plasma cells): 4 people, 22.22%
- Adenocarcinoma (malignant tumour formed from glandular structures in epithelial tissue): 3 people, 16.67%
- Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 3 people, 16.67%
- Acute Myeloid Leukaemia (In Remission): 2 people, 11.11%
- Nausea (feeling of having an urge to vomit): 2 people, 11.11%
- Type 2 Diabetes: 1 person, 5.56%
- Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 1 person, 5.56%
- Bleeding Disorders: 1 person, 5.56%
- Breast Cancer Female: 1 person, 5.56%
- Chest Pain: 1 person, 5.56%
* Approximation only. Some reports may have incomplete information.
Do you take Brilinta and Compazine?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Brilinta and Compazine:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Brilinta:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Compazine:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Brilinta and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Compazine and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on ticagrelor and prochlorperazine maleate (the active ingredients of Brilinta and Compazine, respectively), and Brilinta and Compazine (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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