Brintellix and Allegra drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Brintellix (vortioxetine hydrobromide) and Allegra (fexofenadine hydrochloride). Common drug interactions include suicidal ideation among females and nausea among males.
The phase IV clinical study analyzes what interactions people have when they take Brintellix and Allegra. It is created by eHealthMe based on reports of 49 people who take the same drugs from the FDA, and is updated regularly.
What is Brintellix?
Brintellix has active ingredients of vortioxetine hydrobromide. It is often used in depression. eHealthMe is studying from 6,748 Brintellix users. Check the latest studies of Brintellix.
What is Allegra?
Allegra has active ingredients of fexofenadine hydrochloride. It is often used in allergies. eHealthMe is studying from 75,497 Allegra users. Check the latest studies of Allegra.
49 people who take Brintellix and Allegra together, and have interactions are studied.

What are the common drug interactions of Brintellix and Allegra, by gender? *:
female:
- Suicidal ideation
- Somnambulism (sleep walking)
- Tremor (trembling or shaking movements in one or more parts of your body)
- Ankle fracture
- Contusion (a type of hematoma of tissue in which capillaries)
- Haemoglobin decreased
- Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
- Insomnia (sleeplessness)
- Pneumonia
- Snoring
male:
- Nausea (feeling of having an urge to vomit)
What are the common drug interactions of Brintellix and Allegra, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Back pain
- Pneumonia
- Malaise (a feeling of general discomfort or uneasiness)
- Anorgasmia (type of sexual dysfunction in which a person cannot achieve orgasm, even with adequate stimulation)
- Decreased interest
- Drug effect decreased
- Libido decreased (loss of interest in sex)
- Nausea (feeling of having an urge to vomit)
- Prolactin-producing pituitary tumour
- Restless legs syndrome (a powerful urge to move your legs)
40-49:
- Injection site reaction
- Anxiety
- Myalgia (muscle pain)
- Panic attack
- Periarthritis (inflammation of the external coats of an artery and of the tissues around the artery)
- Speech disorder
- Stress
50-59:
- Migraine (headache)
- Parathyroid disorder
- Restless legs syndrome (a powerful urge to move your legs)
- Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
- Somnambulism (sleep walking)
- Suicidal ideation
- Ankle fracture
- Back pain
- Fall
- Haemoglobin decreased
60+:
- Asthma
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
- Nausea (feeling of having an urge to vomit)
- Oesophagitis (inflammation of oesophagus)
- Cough
What are the existing conditions these people have? *
- Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 39 people, 79.59%
- Cataplexy (loss of muscle tone accompanied by full conscious awareness): 14 people, 28.57%
- Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 5 people, 10.20%
- Tremor (trembling or shaking movements in one or more parts of your body): 4 people, 8.16%
- Seasonal Allergy (allergic condition due to certain season): 4 people, 8.16%
- Rickets (softening of bones): 4 people, 8.16%
- Oedema (fluid collection in tissue): 4 people, 8.16%
- Heart Rate Increased: 4 people, 8.16%
- Constipation: 4 people, 8.16%
- Restless Leg Syndrome (a powerful urge to move your legs): 3 people, 6.12%
* Approximation only. Some reports may have incomplete information.
Do you take Brintellix and Allegra?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Brintellix (6,748 reports)
- Allegra (75,497 reports)
Browse all drug interactions of Brintellix and Allegra:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Brintellix:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Allegra:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Brintellix and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Allegra and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on vortioxetine hydrobromide and fexofenadine hydrochloride (the active ingredients of Brintellix and Allegra, respectively), and Brintellix and Allegra (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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