Brintellix and Botox drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Brintellix (vortioxetine hydrobromide) and Botox (botulinum toxin type a). Common drug interactions include dysgeusia among females and headache among males.

The phase IV clinical study analyzes what interactions people have when they take Brintellix and Botox. It is created by eHealthMe based on reports of 19 people who take the same drugs from the FDA, and is updated regularly.

What is Brintellix?

Brintellix has active ingredients of vortioxetine hydrobromide. It is often used in depression. eHealthMe is studying from 6,748 Brintellix users. Check the latest studies of Brintellix.

What is Botox?

Botox has active ingredients of botulinum toxin type a. It is often used in migraine. eHealthMe is studying from 70,513 Botox users. Check the latest studies of Botox.

On Jul, 09, 2026

19 people who take Brintellix and Botox together, and have interactions are studied.

What are the common drug interactions of Brintellix and Botox, by gender? *:

female:

Dysgeusia (disorder of the sense of taste)
Photopsia (presence of perceived flashes of light)
Muscle spasms (muscle contraction)
Suicidal ideation
Vitamin d decreased
Constipation
Parosmia (distortion of the sense of smell, as in smelling odours that are not present)
Abdominal discomfort
Abdominal distension
Abdominal pain

male:

Headache (pain in head)
Precancerous mucosal lesion
Dysphonia (speech disorder attributable to a disorder of phonation)
Enuresis (repeated inability to control urination)
Eyelid ptosis (falling of the upper or lower eyelid)
Mood altered (changes in mood)
Nasopharyngitis (inflammation of the nasopharynx)
Nausea (feeling of having an urge to vomit)
Nightmare (unpleasant dream)
Oropharyngeal pain

What are the common drug interactions of Brintellix and Botox, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Allergy to chemicals
Bronchitis chronic (inflammation of the mucous membrane in the bronchial tubes- chronic)
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Nightmare (unpleasant dream)
Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
Stress
Therapeutic response unexpected

40-49:

Dysgeusia (disorder of the sense of taste)
Photopsia (presence of perceived flashes of light)
Constipation
Parosmia (distortion of the sense of smell, as in smelling odours that are not present)
Abdominal distension
Abdominal pain
Asthenia (weakness)
Asthma
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Dysmenorrhoea (painful menstruation)

50-59:

Bowel movement irregularity
Burning sensation
Drug hypersensitivity
Drug ineffective
Gingivitis (inflammation of gums)
Mouth ulceration (mouth ulcers)
Oral discomfort (pain or irritation in mouth)
Rash
Urticaria (rash of round, red welts on the skin that itch intensely)
Vitamin d decreased

60+:

Confusional state
Diplopia (double vision)
Visual brightness
Drug ineffective
Dysphagia (a condition in which swallowing is difficult or painful)
Dysphonia (speech disorder attributable to a disorder of phonation)
Eyelid ptosis (falling of the upper or lower eyelid)
Headache (pain in head)
Oropharyngeal pain
Viith nerve paralysis

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 9 people, 47.37%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 6 people, 31.58%
Gastritis (inflammation of stomach): 3 people, 15.79%
Bruxism (habitual grinding of the teeth, typically during sleep): 3 people, 15.79%
Insomnia (sleeplessness): 3 people, 15.79%
Neuralgia (pain in one or more nerves): 2 people, 10.53%
Sleep Disorder: 2 people, 10.53%
Spinal Disorder (disease of spine a back bone): 2 people, 10.53%
Back Pain: 1 person, 5.26%
Birth Control: 1 person, 5.26%

* Approximation only. Some reports may have incomplete information.

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