Brintellix and Morphine sulfate drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Brintellix (vortioxetine hydrobromide) and Morphine sulfate (morphine sulfate). Common drug interactions include drug ineffective among females and chest pain among males.

The phase IV clinical study analyzes what interactions people have when they take Brintellix and Morphine sulfate. It is created by eHealthMe based on reports of 17 people who take the same drugs from the FDA, and is updated regularly.

What is Brintellix?

Brintellix has active ingredients of vortioxetine hydrobromide. It is often used in depression. eHealthMe is studying from 6,749 Brintellix users. Check the latest studies of Brintellix.

What is Morphine sulfate?

Morphine sulfate has active ingredients of morphine sulfate. It is often used in pain. eHealthMe is studying from 87,262 Morphine sulfate users. Check the latest studies of Morphine sulfate.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

17 people who take Brintellix and Morphine sulfate together, and have interactions are studied.

Brintellix and Morphine sulfate drug interactions.

What are the common drug interactions of Brintellix and Morphine Sulfate, by gender? *:

female:

Drug ineffective
Fall
Head injury
Hyperhidrosis (abnormally increased sweating)
Muscle twitching
Nausea (feeling of having an urge to vomit)
Restlessness (not able to rest)
Serotonin syndrome (occurs when two drugs that affect the body's level of serotonin are taken together at the same time)
Somnolence (a state of near-sleep, a strong desire for sleep)
Sudden onset of sleep

male:

Chest pain
Fatigue (feeling of tiredness)
Foot deformity (functional disability of foot)
Headache (pain in head)
Surgery

What are the common drug interactions of Brintellix and Morphine Sulfate, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Somnolence (a state of near-sleep, a strong desire for sleep)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Tremor (trembling or shaking movements in one or more parts of your body)
Hyperhidrosis (abnormally increased sweating)
Muscle twitching
Restlessness (not able to rest)
Serotonin syndrome (occurs when two drugs that affect the body's level of serotonin are taken together at the same time)

40-49:

n/a

50-59:

n/a

60+:

Pancreatitis (inflammation of pancreas)
Abdominal pain
Foot deformity (functional disability of foot)
Headache (pain in head)
Nausea (feeling of having an urge to vomit)
Vomiting

What are the existing conditions these people have? *

High Blood Cholesterol: 6 people, 35.29%
Hyperkalemia (damage to or disease of the kidney): 4 people, 23.53%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 3 people, 17.65%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 3 people, 17.65%
Wheezing (a high-pitched whistling sound made while you breath): 1 person, 5.88%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 5.88%
Borderline Personality Disorder: 1 person, 5.88%
Cholangiocarcinoma (a cancer that forms glands or secretes significant amounts of mucins): 1 person, 5.88%
Diabetes: 1 person, 5.88%
Dry Eyes (lack of adequate tears): 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

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