Brintellix and Prozac drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Brintellix (vortioxetine hydrobromide) and Prozac (fluoxetine hydrochloride). Common drug interactions include chronic kidney disease among females and nausea among males.

The phase IV clinical study analyzes what interactions people have when they take Brintellix and Prozac. It is created by eHealthMe based on reports of 89 people who take the same drugs from the FDA, and is updated regularly.

What is Brintellix?

Brintellix has active ingredients of vortioxetine hydrobromide. It is often used in depression. eHealthMe is studying from 6,748 Brintellix users. Check the latest studies of Brintellix.

What is Prozac?

Prozac has active ingredients of fluoxetine hydrochloride. It is often used in depression. eHealthMe is studying from 82,988 Prozac users. Check the latest studies of Prozac.

On Jul, 17, 2026

89 people who take Brintellix and Prozac together, and have interactions are studied.

Brintellix and Prozac drug interactions.

What are the common drug interactions of Brintellix and Prozac, by gender? *:

female:

Chronic kidney disease
Coagulopathy (blood's ability to clot is impaired)
Confusional state
Crying
Deafness
Depressed mood
Depressive symptom
Drug hypersensitivity
Dysarthria (speech disorder)
Ear infection

male:

Nausea (feeling of having an urge to vomit)
Vomiting
Gastric disorder (disease of stomach)
Hyperhidrosis (abnormally increased sweating)
Presyncope
Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
Agoraphobia (extreme or irrational fear of crowded spaces or enclosed public places)
Alcohol abuse
Blunted affect (lack of emotional reactivity)
Depressed mood

What are the common drug interactions of Brintellix and Prozac, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Hallucination, visual (seeing things that aren't there)
Insomnia (sleeplessness)
Irritability
Myalgia (muscle pain)
Type 2 diabetes mellitus
Weight increased
Abnormal dreams
Drug ineffective
Hallucination, auditory (perceiving sounds without auditory stimulus)

20-29:

Hyperhidrosis (abnormally increased sweating)
Pain
Presyncope
Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
Vomiting
Anger
Tearfulness (excess tearing)

30-39:

Endometriosis (appearance of endometrial tissue outside the uterus and causing pelvic pain)
Memory impairment
Myositis (inflammation of the muscles)
Obsessive rumination (thinking and worry or rumination is an inability to gain control over recurrent, distressing thoughts, images)
Papilloma viral infection
Psychotic disorder
Salivary hypersecretion (excess saliva secretion)
Trismus (reduced opening of the jaws)
Nightmare (unpleasant dream)
Seizure (abnormal excessive or synchronous neuronal activity in the brain)

40-49:

Depressed mood
Agoraphobia (extreme or irrational fear of crowded spaces or enclosed public places)
Alcohol abuse
Blunted affect (lack of emotional reactivity)
Generalised anxiety disorder (excessive, uncontrollable, unexplained and often irrational worry)
Homeless
Impulse-control disorder
Logorrhoea (excessive, uncontrollable, or incoherent talkativeness)
Loss of employment
Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)

50-59:

Drug ineffective
Suicidal ideation
Alopecia (absence of hair from areas of the body)
Bowel movement irregularity
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Depressive symptom
Drug hypersensitivity
Haemoglobin decreased
Headache (pain in head)
Hypoaesthesia (reduced sense of touch or sensation)

60+:

Abdominal pain upper
Cataplexy (loss of muscle tone accompanied by full conscious awareness)
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Renal failure (kidney dysfunction)
Serotonin syndrome (occurs when two drugs that affect the body's level of serotonin are taken together at the same time)
Tardive dyskinesia (a disorder that involves involuntary movements)
Chronic kidney disease
Drug ineffective
Fall
Foot deformity (functional disability of foot)

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 50 people, 56.18%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 29 people, 32.58%
Major Depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings): 7 people, 7.87%
Multiple Myeloma (cancer of the plasma cells): 6 people, 6.74%
Hypersensitivity: 5 people, 5.62%

* Approximation only. Some reports may have incomplete information.

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