Noxafil and Actigall drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Noxafil (posaconazole) and Actigall (ursodiol). Common drug interactions include blood alkaline phosphatase increased among females and pneumonia among males.

The phase IV clinical study analyzes what interactions people have when they take Noxafil and Actigall. It is created by eHealthMe based on reports of 54 people who take the same drugs from the FDA, and is updated regularly.

What is Noxafil?

Noxafil has active ingredients of posaconazole. eHealthMe is studying from 5,919 Noxafil users. Check the latest studies of Noxafil.

What is Actigall?

Actigall has active ingredients of ursodiol. It is often used in gallstones. eHealthMe is studying from 2,162 Actigall users. Check the latest studies of Actigall.

On Jul, 17, 2026

54 people who take Noxafil and Actigall together, and have interactions are studied.

What are the common drug interactions of Noxafil and Actigall, by gender? *:

female:

Blood alkaline phosphatase increased
Blood bilirubin increased
Cardiac failure congestive
Cellulitis (infection under the skin)
Chronic hepatic failure (long lasting liver failure)
Coagulopathy (blood's ability to clot is impaired)
Constipation
Cough
Cytomegalovirus viraemia (cytomegalo virus in blood stream)
Decreased appetite

male:

Pneumonia
Diarrhoea
Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)
Death
Failure to thrive (inadequate weight gain and physical growth in children)
Fall
Febrile neutropenia (fever with reduced white blood cells)
Ileus (a painful obstruction of the ileum or other part of the intestine)
Lung infection
Nausea (feeling of having an urge to vomit)

What are the common drug interactions of Noxafil and Actigall, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Back pain
Headache (pain in head)
Hypogammaglobulinaemia (an abnormally low concentration of gamma globulin in the blood and increased risk of infection)
Hypotension (abnormally low blood pressure)

10-19:

n/a

20-29:

Nausea (feeling of having an urge to vomit)
Cytomegalovirus viraemia (cytomegalo virus in blood stream)
Dehydration (dryness resulting from the removal of water)
Headache (pain in head)
Hypophagia (reduced food intake)
Lactic acidosis (low ph in body tissues)
Oral herpes (viral infection of mouth)
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Poor peripheral circulation
Staphylococcal infection (an infection with staphylococcus bacteria)

30-39:

Cardiac failure congestive
Death
Disseminated intravascular coagulation (systemic activation of blood coagulation)
Febrile neutropenia (fever with reduced white blood cells)
Multi-organ failure (multisystem organ failure)
Sepsis (a severe blood infection that can lead to organ failure and death)
Acute graft versus host disease in liver (acute complication in liver following an allogeneic tissue/blood transplant)
Acute graft versus host disease in skin (acute complication on skin following an allogeneic tissue/blood transplant)
Acute myeloid leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts)
Eye disorder

40-49:

Sepsis (a severe blood infection that can lead to organ failure and death)
Acinetobacter bacteraemia (infection of bacteria)
Anaemia (lack of blood)
Blood albumin decreased
Blood alkaline phosphatase increased
Blood calcium decreased
Blood lactate dehydrogenase increased
Blood potassium decreased
Blood pressure decreased
Blood urea increased

50-59:

Leukaemia recurrent (repeat cancer of bone marrow or blood cells)
Meningitis (inflammation of the protective membranes covering the brain and spinal cord, known collectively as the meninges)
Muscular weakness (muscle weakness)
Night sweats (sweating in night)
Pneumonia
Pyrexia (fever)
Rash
Stomatitis (inflammation of mucous membrane of mouth)
Thrombocytopenia (decrease of platelets in blood)
Alopecia (absence of hair from areas of the body)

60+:

Vomiting
Diarrhoea
Platelet count decreased
Alanine aminotransferase increased
Atelectasis (partial or complete collapse of the lung)
Blood alkaline phosphatase increased
Blood bilirubin increased
Cardiac arrest
Cellulitis (infection under the skin)
Chronic hepatic failure (long lasting liver failure)

What are the existing conditions these people have? *

Nausea (feeling of having an urge to vomit): 16 people, 29.63%
Nausea And Vomiting: 13 people, 24.07%
Graft Versus Host Disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body): 10 people, 18.52%
Pain: 8 people, 14.81%
Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 7 people, 12.96%
Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 7 people, 12.96%
Constipation: 5 people, 9.26%
Acute Graft Versus Host Disease (acute complication following an allogeneic tissue/blood transplant): 5 people, 9.26%
Viral Infection: 4 people, 7.41%
Graft Versus Host Disease In Skin (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the skin): 4 people, 7.41%

* Approximation only. Some reports may have incomplete information.

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