Gengraf and Pain - a phase IV clinical study of FDA data

Summary:

Pain is reported as a side effect among people who take Gengraf (cyclosporine), especially for people who are male, 30-39 old, also take Lasix, and have Computerised tomogram abdomen.

The phase IV clinical study analyzes which people have Pain when taking Gengraf. It is created by eHealthMe based on reports of 932 people who have side effects when taking Gengraf from the FDA, and is updated regularly.

What is Gengraf?

Gengraf has active ingredients of cyclosporine. eHealthMe is studying from 960 Gengraf users. Check the latest studies of Gengraf.

What is Pain?

Pain is found to be associated with 3,806 drugs and 5,872 conditions by eHealthMe. Check the latest studies of Pain.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Jul, 17, 2026

932 people reported to have side effects when taking Gengraf.
Among them, 39 people (4.18%) have Pain.

Among these 39 people:

What is the gender of people who have Pain when taking Gengraf? *

female: 43.24 %
male: 56.76 %

What is the age of people who have Pain when taking Gengraf? *

What are other drugs people take besides Gengraf? *

What are other side effects people have besides Pain? *

Stress And Anxiety: 19 people, 48.72%
Weakness: 17 people, 43.59%
Joint Pain: 15 people, 38.46%
Pain In Extremity: 15 people, 38.46%
Injury: 14 people, 35.90%
Scar: 13 people, 33.33%
Skin Induration (an abnormally hard spot or area on the skin): 12 people, 30.77%
Nephrogenic Systemic Fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease): 12 people, 30.77%
Skin Hypertrophy (skin cells enlarges): 12 people, 30.77%
Oedema Peripheral (superficial swelling): 11 people, 28.21%

What are the existing conditions these people have? *

Nuclear Magnetic Resonance Imaging Brain: 5 people, 12.82%
Nuclear Magnetic Resonance Imaging Abdominal: 5 people, 12.82%
Computerised Tomogram Abdomen: 5 people, 12.82%
Immunodeficiency Disorders: 4 people, 10.26%
Joint Pain: 2 people, 5.13%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 2.56%
Rashes (redness): 1 person, 2.56%
Psoriasis (immune-mediated disease that affects the skin): 1 person, 2.56%
Polyarthritis (arthritis which involves 5 or more joints simultaneously): 1 person, 2.56%
Pain In Extremity: 1 person, 2.56%

* Approximation only. Some reports may have incomplete information.

Do you take Gengraf and have Pain?

- Check whether Pain is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Gengraf:

Gengraf (960 reports)

Pain treatments and more:

Pain (1,140,596 reports)

Browse all side effects of Gengraf:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Pain:

Pain (3,806 drugs)

Browse all the conditions that are associated with Pain:

Pain (5,872 conditions)

Related publications that referenced our studies

O’Brien FE, O’Connor RM, Clarke G, Donovan MD, Dinan TG, Griffin BT, Cryan JF, "The P-glycoprotein inhibitor cyclosporin A differentially influences behavioural and neurochemical responses to the antidepressant escitalopram", Behavioural brain research, 2014 Mar .
O’Brien FE, O’Connor RM, Clarke G, Donovan MD, Dinan TG, Griffin BT, Cryan JF, "The P-glycoprotein inhibitor cyclosporin A differentially influences behavioural and neurochemical responses to the antidepressant escitalopram", Behavioural brain research, 2014 Mar .

How the study uses the data?

The study uses data from the FDA. It is based on cyclosporine (the active ingredients of Gengraf) and Gengraf (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.