Vyvgart and Weight increased - a phase IV clinical study of FDA data

Summary:

Weight increased is reported as a side effect among people who take Vyvgart (efgartigimod alfa), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Mestinon, and have Myasthenia gravis.

The phase IV clinical study analyzes which people have Weight increased when taking Vyvgart. It is created by eHealthMe based on reports of 3,254 people who have side effects when taking Vyvgart from the FDA, and is updated regularly.

What is Vyvgart?

Vyvgart has active ingredients of efgartigimod alfa. eHealthMe is studying from 3,254 Vyvgart users. Check the latest studies of Vyvgart.

What is Weight increased?

Weight increased is found to be associated with 2,889 drugs and 3,962 conditions by eHealthMe. Check the latest studies of Weight increased.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

3,254 people reported to have side effects when taking Vyvgart.
Among them, 41 people (1.26%) have Weight increased.

Among these 41 people:

How long have people been on Vyvgart when they have Weight increased? *

What is the gender of people who have Weight increased when taking Vyvgart? *

female: 66.67 %
male: 33.33 %

What is the age of people who have Weight increased when taking Vyvgart? *

What are other drugs people take besides Vyvgart? *

What are other side effects people have besides Weight increased? *

Weakness: 20 people, 48.78%
Myasthenia Gravis (a chronic condition that causes muscles to tire and weaken easily): 17 people, 41.46%
Fatigue (feeling of tiredness): 16 people, 39.02%
Dyspnea (difficult or laboured breathing): 12 people, 29.27%
Fall: 11 people, 26.83%
Nausea (feeling of having an urge to vomit): 9 people, 21.95%
Hypotension (abnormally low blood pressure): 9 people, 21.95%
Diarrhea: 8 people, 19.51%
Swallowing Difficulty: 8 people, 19.51%
Eyelid Ptosis (falling of the upper or lower eyelid): 7 people, 17.07%

What are the existing conditions these people have? *

Myasthenia Gravis (a chronic condition that causes muscles to tire and weaken easily): 39 people, 95.12%
Neuralgia (pain in one or more nerves): 2 people, 4.88%
Headache (pain in head): 2 people, 4.88%
Full Blood Count Abnormal: 2 people, 4.88%
Type 2 Diabetes: 1 person, 2.44%
Nausea (feeling of having an urge to vomit): 1 person, 2.44%
High Blood Pressure: 1 person, 2.44%
High Blood Cholesterol: 1 person, 2.44%

* Approximation only. Some reports may have incomplete information.

Do you take Vyvgart and have Weight increased?

- Check whether Weight increased is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Vyvgart:

Vyvgart (3,254 reports)

Weight increased treatments and more:

Weight increased (279,371 reports)

Browse all side effects of Vyvgart:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Weight increased:

Weight increased (2,889 drugs)

Browse all the conditions that are associated with Weight increased:

Weight increased (3,962 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on efgartigimod alfa (the active ingredients of Vyvgart) and Vyvgart (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.