Bromhexine hydrochloride and Diflucan drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Bromhexine hydrochloride (bromhexine hydrochloride) and Diflucan (fluconazole). Common drug interactions include abdominal pain among females and pneumonia among males.

The phase IV clinical study analyzes what interactions people have when they take Bromhexine hydrochloride and Diflucan. It is created by eHealthMe based on reports of 24 people who take the same drugs from the FDA, and is updated regularly.

What is Bromhexine hydrochloride?

Bromhexine hydrochloride has active ingredients of bromhexine hydrochloride. It is often used in cough. eHealthMe is studying from 935 Bromhexine hydrochloride users. Check the latest studies of Bromhexine hydrochloride.

What is Diflucan?

Diflucan has active ingredients of fluconazole. It is often used in vaginal yeast infection. eHealthMe is studying from 28,471 Diflucan users. Check the latest studies of Diflucan.



On Jul, 10, 2026

24 people who take Bromhexine hydrochloride and Diflucan together, and have interactions are studied.

Bromhexine hydrochloride and Diflucan drug interactions.

What are the common drug interactions of Bromhexine Hydrochloride and Diflucan, by gender? *:

female:

  1. Abdominal pain
  2. Pyrexia (fever)
  3. Anaemia (lack of blood)
  4. Colitis (inflammation of colon)
  5. Colitis ulcerative (inflammation of colon with ulcer)
  6. Constipation
  7. Drug ineffective
  8. Erythema (redness of the skin)
  9. Female genital tract fistula (passage in genital tract of female)
  10. Frequent bowel movements

male:

  1. Pneumonia
  2. Renal failure acute (rapid kidney dysfunction)
  3. Atrioventricular block complete (heart block complete)
  4. Blood renin activity increased
  5. Blood urea increased
  6. Dehydration (dryness resulting from the removal of water)
  7. Haemoglobin decreased
  8. Hepatic function abnormal
  9. Oxygen saturation decreased
  10. Protein total decreased

What are the common drug interactions of Bromhexine Hydrochloride and Diflucan, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Cardiac failure
  2. Diarrhoea
  3. Febrile neutropenia (fever with reduced white blood cells)
  4. Haemoglobin decreased
  5. Hepatic failure (liver failure)
  6. Hypocalcaemia (levels of calcium in blood serum are abnormally low)
  7. Hypokalaemia (low potassium)
  8. Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood)
  9. Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
  10. Oedema (fluid collection in tissue)

30-39:

  1. Blood alkaline phosphatase nos increased
  2. Blood bilirubin increased
  3. Hepatic function abnormal
  4. Liver transplant rejection (failure of liver transplant)

40-49:

n/a

50-59:

n/a

60+:

  1. Pyrexia (fever)
  2. Abdominal pain
  3. Haematochezia (passage of stools containing blood)
  4. Headache (pain in head)
  5. Nausea (feeling of having an urge to vomit)
  6. Paraesthesia oral (sensation of tingling, tickling, prickling, pricking, or burning of a person's oral with no apparent long-term physical effect)
  7. Pneumonia
  8. Radiculopathy (a set of conditions in which one or more nerves is affected and does not work properly)
  9. Rectal haemorrhage (bleeding from anus)
  10. Renal failure acute (rapid kidney dysfunction)

What are the existing conditions these people have? *

  1. Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 6 people, 25.00%
  2. Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 5 people, 20.83%
  3. Seizures (abnormal excessive or synchronous neuronal activity in the brain): 5 people, 20.83%
  4. Colitis (inflammation of colon): 5 people, 20.83%
  5. Allergies: 5 people, 20.83%
  6. Fever: 4 people, 16.67%
  7. Urethral Disorder: 3 people, 12.50%
  8. Oedema (fluid collection in tissue): 2 people, 8.33%
  9. Lung Infiltration (a substance that normally includes fluid, inflammatory exudates or cells that fill a region of lung): 2 people, 8.33%
  10. Acute Lymphocytic Leukaemia Recurrent (cancer in which the bone marrow makes too many lymphocytes-recurrent): 2 people, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Bromhexine hydrochloride and Diflucan?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Bromhexine hydrochloride and Diflucan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Bromhexine hydrochloride:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Diflucan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Bromhexine hydrochloride and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Diflucan and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on bromhexine hydrochloride and fluconazole (the active ingredients of Bromhexine hydrochloride and Diflucan, respectively), and Bromhexine hydrochloride and Diflucan (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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