Bumetanide and Cefazolin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Bumetanide (bumetanide) and Cefazolin (cefazolin sodium). Common drug interactions include rales among females and atrial fibrillation among males.

The phase IV clinical study analyzes what interactions people have when they take Bumetanide and Cefazolin. It is created by eHealthMe based on reports of 80 people who take the same drugs from the FDA, and is updated regularly.

What is Bumetanide?

Bumetanide has active ingredients of bumetanide. It is often used in fluid retention. eHealthMe is studying from 20,532 Bumetanide users. Check the latest studies of Bumetanide.

What is Cefazolin?

Cefazolin has active ingredients of cefazolin sodium. It is often used in infection. eHealthMe is studying from 15,157 Cefazolin users. Check the latest studies of Cefazolin.



On Jul, 07, 2026

80 people who take Bumetanide and Cefazolin together, and have interactions are studied.

Bumetanide and Cefazolin drug interactions.

What are the common drug interactions of Bumetanide and Cefazolin, by gender? *:

female:

  1. Rales (an abnormal respiratory sound characterized by fine crackles)
  2. Convulsions (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled of muscles contract and relax rapidly and repeatedly)
  3. Nausea (feeling of having an urge to vomit)
  4. Renal failure (kidney dysfunction)
  5. Rhonchi (abnormal breath sounds)
  6. Staphylococcal infection (an infection with staphylococcus bacteria)
  7. Depression
  8. Red blood cell count decreased
  9. Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
  10. Erythema (redness of the skin)

male:

  1. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  2. Chronic kidney disease
  3. Device occlusion
  4. Drug dependence
  5. Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
  6. Eating disorder
  7. Encephalopathy (functioning of the brain is affected by some agent or condition)
  8. Hypokalaemia (low potassium)
  9. Impaired driving ability
  10. Lethargy (tiredness)

What are the common drug interactions of Bumetanide and Cefazolin, by age (0-1 to 60+)? *:

0-1:

  1. Asthenia (weakness)
  2. Cerebral palsy
  3. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
  4. Choking sensation (feeling of obstruction in respiratory system)
  5. Developmental delay
  6. Hemiplegia (paralysis of one side of the body)
  7. Hypotension (abnormally low blood pressure)
  8. Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
  9. Visual impairment

2-9:

  1. Hypotension (abnormally low blood pressure)
  2. Abdominal distension
  3. Acute respiratory failure
  4. Anaemia (lack of blood)
  5. Angioplasty
  6. Arteriovenous fistula
  7. Asthenia (weakness)
  8. Atrial flutter (an abnormal heart rhythm that occurs in the atria of the heart)
  9. Atrial tachycardia (rhythm disturbance that arises in the atria)
  10. Cardio-respiratory arrest (sudden dysfunction of heart and lungs)

10-19:

  1. Anaphylactic reaction (serious allergic reaction)
  2. Pulmonary oedema (fluid accumulation in the lungs)
  3. Asthenia (weakness)
  4. Cardiomyopathy (weakening of the heart muscle)
  5. Dyspnoea (difficult or laboured respiration)
  6. Enterobacter pneumonia (lung inflammation caused by bacteria of the family enterobacteriaceae)
  7. Epistaxis (bleed from the nose)
  8. Heart rate decreased
  9. Hyperglycaemia (high blood sugar)
  10. Hypotension (abnormally low blood pressure)

20-29:

  1. Chest pain
  2. Epistaxis (bleed from the nose)
  3. Haematemesis (vomiting of blood)
  4. Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
  5. Pseudomonal bacteraemia (p. aeruginosa cause of bacterial infections of the blood)
  6. Pyrexia (fever)

30-39:

  1. Chronic kidney disease
  2. Renal failure (kidney dysfunction)
  3. Anxiety
  4. Depression

40-49:

  1. Nausea (feeling of having an urge to vomit)
  2. Erythema (redness of the skin)
  3. Headache (pain in head)
  4. Papilloedema (optic disc swelling)
  5. Alanine aminotransferase increased
  6. Aspartate aminotransferase increased
  7. Blood alkaline phosphatase increased
  8. Creatine phosphokinase decreased
  9. Haematocrit decreased
  10. Haemoglobin decreased

50-59:

  1. Drug ineffective
  2. Genital abscess (build up of pus in genital)
  3. Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
  4. Necrotising fasciitis (an uncommon life-threatening soft-tissue infection)
  5. Nephrogenic anaemia (anaemia due to kidney disease)
  6. Nephropathy toxic (damage to kidney due to toxins)
  7. Panic attack
  8. Renal tubular necrosis (death of kidney tubules)
  9. Respiratory disorder (respiratory disease)
  10. Sputum culture positive

60+:

  1. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  2. Pyrexia (fever)
  3. Malnutrition (a condition that results from eating a diet in which certain nutrients are lacking)
  4. Rales (an abnormal respiratory sound characterized by fine crackles)
  5. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
  6. Convulsions (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled of muscles contract and relax rapidly and repeatedly)
  7. Death
  8. Haematocrit decreased
  9. Haemoglobin decreased
  10. Neutropenia (an abnormally low number of neutrophils)

What are the existing conditions these people have? *

  1. Pain: 17 people, 21.25%
  2. High Blood Cholesterol: 11 people, 13.75%
  3. Nausea (feeling of having an urge to vomit): 9 people, 11.25%
  4. High Blood Pressure: 8 people, 10.00%
  5. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 7 people, 8.75%
  6. Blood Pressure Abnormal: 7 people, 8.75%
  7. Sedation: 6 people, 7.50%
  8. Cardiac Failure: 6 people, 7.50%
  9. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 5 people, 6.25%
  10. Depression: 5 people, 6.25%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Bumetanide and Cefazolin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Bumetanide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Cefazolin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Bumetanide and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Cefazolin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on bumetanide and cefazolin sodium (the active ingredients of Bumetanide and Cefazolin, respectively), and Bumetanide and Cefazolin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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