Bumex and Leflunomide drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Bumex (bumetanide) and Leflunomide (leflunomide). Common drug interactions include pneumonia among females and chest discomfort among males.

The phase IV clinical study analyzes what interactions people have when they take Bumex and Leflunomide. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.

What is Bumex?

Bumex has active ingredients of bumetanide. It is often used in swelling. eHealthMe is studying from 9,210 Bumex users. Check the latest studies of Bumex.

What is Leflunomide?

Leflunomide has active ingredients of leflunomide. It is often used in rheumatoid arthritis. eHealthMe is studying from 82,105 Leflunomide users. Check the latest studies of Leflunomide.

On Jul, 08, 2026

16 people who take Bumex and Leflunomide together, and have interactions are studied.

Bumex and Leflunomide drug interactions.

What are the common drug interactions of Bumex and Leflunomide, by gender? *:

female:

Pneumonia
Pyelonephritis (inflammation of kidney caused by bacteria)
Abdominal pain upper
Adverse event
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Blood magnesium increased
Blood potassium decreased
Breast abscess
Breast cyst
C-reactive protein increased

male:

Chest discomfort
Cough
Death
Dyspnoea (difficult or laboured respiration)
Headache (pain in head)
Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
Nausea (feeling of having an urge to vomit)
Oedema peripheral (superficial swelling)
Oxygen saturation decreased

What are the common drug interactions of Bumex and Leflunomide, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Drug ineffective
Fatigue (feeling of tiredness)
Influenza like illness
Memory impairment
Myalgia (muscle pain)
Somnolence (a state of near-sleep, a strong desire for sleep)

60+:

Dyspnoea (difficult or laboured respiration)
Nausea (feeling of having an urge to vomit)
C-reactive protein increased
Chest discomfort
Chest pain
Constipation
Cough
Death
Diarrhoea
Dry skin

What are the existing conditions these people have? *

Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 4 people, 25.00%
Sarcoidosis (an inflammatory disease that affects multiple organs in the body, but mostly the lungs and lymph glands): 2 people, 12.50%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 2 people, 12.50%
Upper Respiratory Tract Congestion: 1 person, 6.25%
Dizziness: 1 person, 6.25%
Autoimmune Hepatitis: 1 person, 6.25%
Cardiac Failure Congestive: 1 person, 6.25%
Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 1 person, 6.25%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 1 person, 6.25%
Coronary Heart Disease (narrowing or blockage of the coronary arteries): 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

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