Buspar and Cimetidine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Buspar (buspirone hydrochloride) and Cimetidine (cimetidine). Common drug interactions include creatine phosphokinase decreased among females and pneumonia among males.

The phase IV clinical study analyzes what interactions people have when they take Buspar and Cimetidine. It is created by eHealthMe based on reports of 40 people who take the same drugs from the FDA, and is updated regularly.

What is Buspar?

Buspar has active ingredients of buspirone hydrochloride. It is often used in stress and anxiety. eHealthMe is studying from 20,462 Buspar users. Check the latest studies of Buspar.

What is Cimetidine?

Cimetidine has active ingredients of cimetidine. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 10,531 Cimetidine users. Check the latest studies of Cimetidine.

On Jul, 10, 2026

40 people who take Buspar and Cimetidine together, and have interactions are studied.

Buspar and Cimetidine drug interactions.

What are the common drug interactions of Buspar and Cimetidine, by gender? *:

female:

Creatine phosphokinase decreased
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Gastritis (inflammation of stomach)
Haematocrit decreased
Haemoglobin decreased
Optic atrophy (the loss of a proportion of optic disc nerve fibres)
Renal failure (kidney dysfunction)
Vision blurred
Abdominal pain
Arthralgia (joint pain)

male:

Pneumonia
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Dental caries
Dyspnoea (difficult or laboured respiration)
Gingival bleeding (bleeding gums)
Hiatus hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm)
Hypercalcaemia (elevated calcium (ca+) level in the blood)
Hypercholesterolaemia (high levels of cholesterol in the blood)
Hypertension (high blood pressure)
Injury

What are the common drug interactions of Buspar and Cimetidine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)

40-49:

Erythema (redness of the skin)
Headache (pain in head)
Nausea (feeling of having an urge to vomit)
Papilloedema (optic disc swelling)
Alanine aminotransferase increased
Aspartate aminotransferase increased
Blood alkaline phosphatase increased
Creatine phosphokinase decreased
Haematocrit decreased
Haemoglobin decreased

50-59:

Axillary pain
Blood albumin decreased
Blood bicarbonate decreased
Blood calcium decreased
Blood magnesium decreased
Blood phosphorus increased
Blood triglycerides increased
Bradycardia (abnormally slow heart action)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Bundle branch block left (absence of transmission of electric impulses from the atrioventricular (av) bundle of his to the left ventricle)

60+:

Pneumonia
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Gingival bleeding (bleeding gums)
Hiatus hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm)
Hypercalcaemia (elevated calcium (ca+) level in the blood)
Hypercholesterolaemia (high levels of cholesterol in the blood)
Hypertension (high blood pressure)
Injury
Lung disorder (lung disease)
Neck injury

What are the existing conditions these people have? *

Depression: 6 people, 15.00%
Multiple Myeloma (cancer of the plasma cells): 4 people, 10.00%
Staphylococcal Osteomyelitis (inflammation of bone or bone marrow, usually due to staphylococcus bacterial infection): 2 people, 5.00%
Sleep Disorder: 2 people, 5.00%
Pain: 2 people, 5.00%
Insomnia (sleeplessness): 2 people, 5.00%
Hypersensitivity: 2 people, 5.00%
Gastric Ulcer (stomach ulcer): 2 people, 5.00%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 2 people, 5.00%

* Approximation only. Some reports may have incomplete information.

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