Flonase and Midazolam drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Flonase (fluticasone propionate) and Midazolam (midazolam). Common drug interactions include chronic kidney disease among females and seizure among males.

The phase IV clinical study analyzes what interactions people have when they take Flonase and Midazolam. It is created by eHealthMe based on reports of 36 people who take the same drugs from the FDA, and is updated regularly.

What is Flonase?

Flonase has active ingredients of fluticasone propionate. It is often used in allergies. eHealthMe is studying from 75,441 Flonase users. Check the latest studies of Flonase.

What is Midazolam?

Midazolam has active ingredients of midazolam. eHealthMe is studying from 11,246 Midazolam users. Check the latest studies of Midazolam.

On Jul, 10, 2026

36 people who take Flonase and Midazolam together, and have interactions are studied.

Flonase and Midazolam drug interactions.

What are the common drug interactions of Flonase and Midazolam, by gender? *:

female:

Chronic kidney disease
Renal failure (kidney dysfunction)
Anaemia (lack of blood)
Arterial haemorrhage
Delirium (wild excitement)
Diarrhoea
Dizziness
Dyspnoea (difficult or laboured respiration)
Fall
Fluid imbalance (imbalance of fluid in body in intake and fluid lost)

male:

Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Chronic kidney disease
Erectile dysfunction
Groin abscess (pus in groin)
Hypokalaemia (low potassium)
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Insomnia (sleeplessness)
Intervertebral disc degeneration (spinal disc degeneration)
Laryngeal cancer (cancer of the larynx)
Obesity (having too much body fat)

What are the common drug interactions of Flonase and Midazolam, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Bacteraemia (presence of bacteria in the blood)
Gastritis (inflammation of stomach)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Haemoglobin decreased
Respiratory disorder (respiratory disease)
Seizure (abnormal excessive or synchronous neuronal activity in the brain)

10-19:

Death

20-29:

Dyspnoea (difficult or laboured respiration)
Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Somnolence (a state of near-sleep, a strong desire for sleep)
Death

30-39:

Balance disorder
Decreased appetite
Insomnia (sleeplessness)
Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Weight decreased

40-49:

Azotaemia (excess of urea or other nitrogenous compounds in the blood)
Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
Chronic kidney disease
Eye swelling
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Nephrogenic anaemia (anaemia due to kidney disease)
Rash pruritic (redness with itching)
Renal cell carcinoma stage i (the tumour is 7 centimetres or smaller and is found only in the kidney)
Renal failure (kidney dysfunction)
Renal pain (kidney pain)

50-59:

Chronic kidney disease
Renal failure (kidney dysfunction)
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Nephrogenic anaemia (anaemia due to kidney disease)
Alopecia universalis (rapid loss of all hair, including eyebrows and eyelashes)
Anal abscess
Cellulitis (infection under the skin)
Perioral dermatitis (facial rash that causes bumps to develop around the mouth)
Psoriasis (immune-mediated disease that affects the skin)
Sacroiliitis (an inflammation of the sacroiliac joint)

60+:

Sepsis (a severe blood infection that can lead to organ failure and death)
Anal abscess
Hypokalaemia (low potassium)
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Intervertebral disc degeneration (spinal disc degeneration)
Laryngeal cancer (cancer of the larynx)
Obesity (having too much body fat)
Osteochondrosis (a family of orthopaedic diseases of the joint that occur in children and adolescents)
Perineal abscess
Pituitary-dependent cushing's syndrome (pituitary dependent hypercortisolism)

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 10 people, 27.78%
Pain: 9 people, 25.00%
High Blood Cholesterol: 6 people, 16.67%
High Blood Pressure: 5 people, 13.89%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 5 people, 13.89%
Type 2 Diabetes: 4 people, 11.11%
Hypersensitivity: 4 people, 11.11%
Diabetes: 4 people, 11.11%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 3 people, 8.33%
Constipation: 3 people, 8.33%

* Approximation only. Some reports may have incomplete information.

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