Buspar and Exelon drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Buspar (buspirone hydrochloride) and Exelon (rivastigmine tartrate). Common drug interactions include death among females and aggression among males.

The phase IV clinical study analyzes what interactions people have when they take Buspar and Exelon. It is created by eHealthMe based on reports of 20 people who take the same drugs from the FDA, and is updated regularly.

What is Buspar?

Buspar has active ingredients of buspirone hydrochloride. It is often used in stress and anxiety. eHealthMe is studying from 20,463 Buspar users. Check the latest studies of Buspar.

What is Exelon?

Exelon has active ingredients of rivastigmine tartrate. It is often used in alzheimer's disease. eHealthMe is studying from 11,060 Exelon users. Check the latest studies of Exelon.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Aug, 28, 2026

20 people who take Buspar and Exelon together, and have interactions are studied.

Buspar and Exelon drug interactions.

What are the common drug interactions of Buspar and Exelon, by gender? *:

female:

  1. Death
  2. Fall
  3. Acute pre-renal failure (prerenal acute renal failure (arf) occurs when a sudden reduction in blood flow to the kidney)
  4. Agitation (state of anxiety or nervous excitement)
  5. Arrhythmia (irregular heartbeat)
  6. Blood cholesterol increased
  7. Blood disorder
  8. Confusion
  9. Confusional state
  10. Contusion (a type of hematoma of tissue in which capillaries)

male:

  1. Aggression
  2. Grand mal convulsion (a type of generalized seizure that affects the entire brain)
  3. Gastric ulcer haemorrhage (bleeding ulcer of stomach)
  4. Hallucination (an experience involving the perception of something not present)
  5. Impulsive behaviour
  6. Muscle rigidity (muscle stiffness)
  7. Myocardial ischaemia (the blood flow through one or more of the blood vessels that lead to heart (coronary arteries) is decreased)
  8. Parkinsonism (degenerative disorder of the central nervous system characterized by tremor and impaired muscular coordination)
  9. Sweating increased (excess sweating)
  10. Tremor (trembling or shaking movements in one or more parts of your body)

What are the common drug interactions of Buspar and Exelon, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Grand mal convulsion (a type of generalized seizure that affects the entire brain)
  2. Blood cholesterol increased
  3. Confusional state
  4. Death
  5. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  6. Gastric ulcer haemorrhage (bleeding ulcer of stomach)
  7. Glucose tolerance impaired (blood glucose is raised beyond normal levels, but not high enough to warrant a diabetes diagnosis)
  8. Glycosuria (excretion of glucose into the urine)
  9. Hypercholesterolaemia (high levels of cholesterol in the blood)
  10. Hyperglycaemia (high blood sugar)

60+:

  1. Death
  2. Acute pre-renal failure (prerenal acute renal failure (arf) occurs when a sudden reduction in blood flow to the kidney)
  3. Hallucination (an experience involving the perception of something not present)
  4. Hyperkalaemia (damage to or disease of the kidney)
  5. Inappropriate antidiuretic hormone secretion
  6. Muscle rigidity (muscle stiffness)
  7. Nausea (feeling of having an urge to vomit)
  8. Orthostatic hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up)
  9. Parkinsonism (degenerative disorder of the central nervous system characterized by tremor and impaired muscular coordination)
  10. Sweating increased (excess sweating)

What are the existing conditions these people have? *

  1. Movement - Unpredictable Or Jerky: 3 people, 15.00%
  2. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 10.00%
  3. High Blood Pressure: 2 people, 10.00%
  4. Depression: 2 people, 10.00%
  5. Weight Decreased: 1 person, 5.00%
  6. Post-Traumatic Stress Disorder: 1 person, 5.00%
  7. Osteoporosis (bones weak and more likely to break): 1 person, 5.00%
  8. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 1 person, 5.00%
  9. Gastrointestinal Disorder (functional problems of gastrointestinal tract): 1 person, 5.00%
  10. Dissociative Identity Disorder: 1 person, 5.00%

* Approximation only. Some reports may have incomplete information.

Do you take Buspar and Exelon?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Buspar and Exelon:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Buspar:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Exelon:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Buspar and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Exelon and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on buspirone hydrochloride and rivastigmine tartrate (the active ingredients of Buspar and Exelon, respectively), and Buspar and Exelon (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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