Buspar and Indocin drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Buspar (buspirone hydrochloride) and Indocin (indomethacin). Common drug interactions include rash among females and blindness cortical among males.
The phase IV clinical study analyzes what interactions people have when they take Buspar and Indocin. It is created by eHealthMe based on reports of 32 people who take the same drugs from the FDA, and is updated regularly.
What is Buspar?
Buspar has active ingredients of buspirone hydrochloride. It is often used in stress and anxiety. eHealthMe is studying from 20,462 Buspar users. Check the latest studies of Buspar.
What is Indocin?
Indocin has active ingredients of indomethacin. It is often used in gout. eHealthMe is studying from 4,559 Indocin users. Check the latest studies of Indocin.
32 people who take Buspar and Indocin together, and have interactions are studied.

What are the common drug interactions of Buspar and Indocin, by gender? *:
female:
- Rash
- Rash papular (redness with papule)
- Rash pruritic (redness with itching)
- Red blood cell count decreased
- Renal failure chronic (long lasting kidney dysfunction)
- Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints)
- Skin discolouration (change of skin colour)
- Substance abuse
- Suicide attempt
- Angina pectoris (chest pain due to ischemia of the heart muscle)
male:
- Blindness cortical
- Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
- Acute myocardial infarction (acute heart attack)
- Adverse event
- Atrioventricular block second degree (heart block second degree)
- Bladder neoplasm (bladder tumour)
- Cardiovascular disorder (heart diseases)
- Carotid artery stenosis (narrowing of carotid artery)
- Circulatory collapse
- Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
What are the common drug interactions of Buspar and Indocin, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
- Diabetic gastroparesis (paralysis of the muscles of the stomach caused by diabetes)
- Hypoglycaemia (deficiency of glucose in the bloodstream)
- Neuropathy peripheral (surface nerve damage)
- Weight decreased
30-39:
n/a
40-49:
- Myalgia (muscle pain)
- Nipple disorder (disease of nipple)
- Osteoarthritis (a joint disease caused by cartilage loss in a joint)
- Osteopenia (a condition where bone mineral density is lower than normal)
- Ovarian failure (ovary is not functioning)
- Pain in extremity
- Palpitations (feelings or sensations that your heart is pounding or racing)
- Radiculitis brachial (inflammation of the spinal nerve roots of brachial plexus)
- Sciatica (a set of symptoms including pain caused by general compression or irritation of one of five spinal nerve roots of each sciatic nerve)
- Spinal osteoarthritis (joint cartilage loss in spine)
50-59:
- Hypertension (high blood pressure)
- Blindness cortical
- Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
- Retinal haemorrhage (bleeding from retina)
- Transient ischaemic attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow))
- Excoriation (to tear or wear off the skin of)
- Erectile dysfunction
- Fat tissue increased
- Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
- Injury
60+:
- Ear pain
- Eye pruritus (eye itching)
- Hyperthyroidism (over activity of the thyroid gland)
- Nasal discomfort
- Rash
- Rash papular (redness with papule)
- Rash pruritic (redness with itching)
- Renal failure chronic (long lasting kidney dysfunction)
- Skin discolouration (change of skin colour)
- Bone disorder
What are the existing conditions these people have? *
- Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 8 people, 25.00%
- High Blood Pressure: 8 people, 25.00%
- Pain: 7 people, 21.88%
- Menopause (end of monthly cycles in women): 7 people, 21.88%
- High Blood Cholesterol: 7 people, 21.88%
- Sleep Disorder: 6 people, 18.75%
- Central Pain Syndrome (neurological condition caused by damage or malfunction in the central nervous system): 6 people, 18.75%
- Inflammation: 5 people, 15.62%
- Headache (pain in head): 3 people, 9.38%
- Depression: 3 people, 9.38%
* Approximation only. Some reports may have incomplete information.
Do you take Buspar and Indocin?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Buspar and Indocin:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Buspar:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Indocin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Buspar and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Indocin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Mantarro S, Tuccori M, Pasqualetti G, Tognini S, Montagnani S, Monzani F, Blandizzi C, "Acute portal vein thrombosis precipitated by indomethacin in a HCV-positive elderly patient", BMC geriatrics, 2012 Nov .
- Mantarro S, Tuccori M, Pasqualetti G, Tognini S, Montagnani S, Monzani F, Blandizzi C, "Acute portal vein thrombosis precipitated by indomethacin in a HCV-positive elderly patient", BMC geriatrics, 2012 Nov .
How the study uses the data?
The study uses data from the FDA. It is based on buspirone hydrochloride and indomethacin (the active ingredients of Buspar and Indocin, respectively), and Buspar and Indocin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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