Buspar and Lopid drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Buspar (buspirone hydrochloride) and Lopid (gemfibrozil). Common drug interactions include urinary tract infection among females and pancreatitis among males.

The phase IV clinical study analyzes what interactions people have when they take Buspar and Lopid. It is created by eHealthMe based on reports of 86 people who take the same drugs from the FDA, and is updated regularly.

What is Buspar?

Buspar has active ingredients of buspirone hydrochloride. It is often used in stress and anxiety. eHealthMe is studying from 20,463 Buspar users. Check the latest studies of Buspar.

What is Lopid?

Lopid has active ingredients of gemfibrozil. It is often used in high blood cholesterol. eHealthMe is studying from 9,700 Lopid users. Check the latest studies of Lopid.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 27, 2026

86 people who take Buspar and Lopid together, and have interactions are studied.

What are the common drug interactions of Buspar and Lopid, by gender? *:

female:

Urinary tract infection
Vomiting
Alopecia (absence of hair from areas of the body)
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Drug maladministration
Dyspnoea (difficult or laboured respiration)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Hepatitis (inflammation of the liver)
Hyperglycaemia (high blood sugar)

male:

Pancreatitis (inflammation of pancreas)
Diarrhoea
Respiratory syncytial virus infection (viral disease of respiratory system)
Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
Suicidal ideation
Vomiting
Arthropathy
Chest discomfort
Coeliac artery stenosis (abnormal narrowing of coeliac artery)
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)

What are the common drug interactions of Buspar and Lopid, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Abdominal pain
Acute coronary syndrome (acute chest pain and other symptoms that happen because the heart does not get blood)
Aphthous stomatitis (mouth ulcer)
Arthralgia (joint pain)
Back pain
Bipolar disorder (mood disorder)
Bronchitis chronic (inflammation of the mucous membrane in the bronchial tubes- chronic)
Cellulitis (infection under the skin)
Chest discomfort

30-39:

Pancreatitis (inflammation of pancreas)
Libido decreased (loss of interest in sex)
Abdominal distension
Blood creatine phosphokinase increased
Blood creatine phosphokinase mb increased
Blood in stool
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Chest pain
Constipation
Cough

40-49:

Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Diarrhoea
Vomiting
Weight increased
Abdominal pain
Dyspnoea (difficult or laboured respiration)
Pancreatitis (inflammation of pancreas)
Arthralgia (joint pain)
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)

50-59:

Hepatic congestion (liver congestion)
Hepatitis (inflammation of the liver)
Inappropriate adh secretion
Intraventricular haemorrhage (intraventricular bleeding)
Loss of consciousness
Peptic ulcer
Pulmonary oedema (fluid accumulation in the lungs)
Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
Subarachnoid haemorrhage (blood leaks into the space between two membranes that surround the brain)
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)

60+:

Bronchial hyperreactivity
Headache (pain in head)
Weakness
Weight increased
Abdominal pain
Abdominal pain upper
Abdominal wall haematoma (abdominal wall blood clotting)
Angioplasty
Aortic dilatation
Arteriosclerosis coronary artery (thickening and hardening of arteries- coronary artery)

What are the existing conditions these people have? *

Depression: 22 people, 25.58%
High Blood Pressure: 12 people, 13.95%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 12 people, 13.95%
Pain: 11 people, 12.79%
Diabetes: 10 people, 11.63%
Hyperlipidaemia (presence of excess lipids in the blood): 9 people, 10.47%
Enlarged Prostate: 8 people, 9.30%
Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 7 people, 8.14%

* Approximation only. Some reports may have incomplete information.

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