Buspar and Nicotine drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Buspar (buspirone hydrochloride) and Nicotine (nicotine). Common drug interactions include skin ulcer among females and bronchitis among males.
The phase IV clinical study analyzes what interactions people have when they take Buspar and Nicotine. It is created by eHealthMe based on reports of 78 people who take the same drugs from the FDA, and is updated regularly.
What is Buspar?
Buspar has active ingredients of buspirone hydrochloride. It is often used in stress and anxiety. eHealthMe is studying from 20,462 Buspar users. Check the latest studies of Buspar.
What is Nicotine?
Nicotine has active ingredients of nicotine. It is often used in quit smoking. eHealthMe is studying from 20,443 Nicotine users. Check the latest studies of Nicotine.
78 people who take Buspar and Nicotine together, and have interactions are studied.

What are the common drug interactions of Buspar and Nicotine, by gender? *:
female:
- Skin ulcer
- Hypersensitivity
- Malaise (a feeling of general discomfort or uneasiness)
- Arterial disorder
- Cataract (clouding of the lens inside the eye)
- Dizziness
- Drug effect decreased
- Joint injury
- Nervousness
- Nicotine dependence
male:
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
- Pneumonia
- Pleural effusion (water on the lungs)
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Arthritis (form of joint disorder that involves inflammation of one or more joints)
- Asthma
- Atelectasis (partial or complete collapse of the lung)
- Bone disorder
- Cardiovascular disorder (heart diseases)
- Cataract (clouding of the lens inside the eye)
What are the common drug interactions of Buspar and Nicotine, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Hypoglycaemia (deficiency of glucose in the bloodstream)
- Seizure (abnormal excessive or synchronous neuronal activity in the brain)
- Torticollis (a twisted neck in which the head is tipped to one side, while the chin is turned to the other)
30-39:
- Drug abuse
- Cellulitis (infection under the skin)
- Hepatitis c
- Hypotension (abnormally low blood pressure)
- Platelet count decreased
- Skin ulcer
- Hepatitis b virus test positive
- Thrombocytopenia (decrease of platelets in blood)
- Suicide attempt
- Abdominal pain
40-49:
- Blood potassium decreased
- Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
- Chronic kidney disease
- Fall
- Hypertension (high blood pressure)
- Intervertebral disc protrusion (spinal disc protrusion)
- Loss of consciousness
- Nicotine dependence
- Pancreatitis (inflammation of pancreas)
- Prostatomegaly (enlargement of the prostate)
50-59:
- Anaphylactic reaction (serious allergic reaction)
- Constipation
- Diarrhoea
- Dry mouth
- Influenza like illness
- Muscle spasms (muscle contraction)
- Neuroleptic malignant syndrome (a life-threatening neurological disorder most often caused by an adverse reaction to neuroleptic or antipsychotic agents)
- Pain in extremity
- Urinary tract disorder
- Vomiting
60+:
- Cataract (clouding of the lens inside the eye)
- Rib fracture
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
- Cardiovascular disorder (heart diseases)
- Dental caries
- Dyspnoea (difficult or laboured respiration)
- Gingival bleeding (bleeding gums)
- Hiatus hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm)
- Hypercalcaemia (elevated calcium (ca+) level in the blood)
- Hypercholesterolaemia (high levels of cholesterol in the blood)
What are the existing conditions these people have? *
- Depression: 9 people, 11.54%
- Muscle Spasms (muscle contraction): 7 people, 8.97%
- Insomnia (sleeplessness): 6 people, 7.69%
- Asthma: 6 people, 7.69%
- Muscle Spasticity (tight or stiff muscles and an inability to control those muscles): 5 people, 6.41%
- Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 5 people, 6.41%
- Migraine (headache): 5 people, 6.41%
- Cellulitis (infection under the skin): 5 people, 6.41%
- Tooth Disorder (tooth disease): 4 people, 5.13%
- Pain: 4 people, 5.13%
* Approximation only. Some reports may have incomplete information.
Do you take Buspar and Nicotine?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Buspar and Nicotine:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Buspar:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Nicotine:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Buspar and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Nicotine and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on buspirone hydrochloride and nicotine (the active ingredients of Buspar and Nicotine, respectively), and Buspar and Nicotine (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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