Buspar and Phentermine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Buspar (buspirone hydrochloride) and Phentermine (phentermine hydrochloride). Common drug interactions include osteoporosis among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Buspar and Phentermine. It is created by eHealthMe based on reports of 99 people who take the same drugs from the FDA, and is updated regularly.

What is Buspar?

Buspar has active ingredients of buspirone hydrochloride. It is often used in stress and anxiety. eHealthMe is studying from 20,462 Buspar users. Check the latest studies of Buspar.

What is Phentermine?

Phentermine has active ingredients of phentermine hydrochloride. It is often used in weight loss. eHealthMe is studying from 19,870 Phentermine users. Check the latest studies of Phentermine.

On Jul, 11, 2026

99 people who take Buspar and Phentermine together, and have interactions are studied.

Buspar and Phentermine drug interactions.

What are the common drug interactions of Buspar and Phentermine, by gender? *:

female:

Osteoporosis (bones weak and more likely to break)
Rectal ulcer haemorrhage (bleeding from rectum ulcer)
Syncope (loss of consciousness with an inability to maintain postural tone)
Systemic lupus erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue)
Fungal infection
Sleep-related eating disorder (abnormal eating patterns during the night)
Vertigo
Chronic fatigue syndrome (disorder that causes extreme fatigue)
Herpes simplex (herpes simplex is a common viral infection)
Temporomandibular joint syndrome (pain at the temporomandibular joint due to various causes of increased muscle tension and spasm. it is believed that syndrome is a physical manifestation of psychological stress)

male:

Chronic kidney disease
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Chest pain
Constipation
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Drug abuser
Drug dependence
Drug ineffective
Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
Dysphagia (a condition in which swallowing is difficult or painful)

What are the common drug interactions of Buspar and Phentermine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Fatigue (feeling of tiredness)
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Pain
Chest pain
Headache (pain in head)
Insomnia (sleeplessness)
Vomiting
Ageusia (loss of taste functions of the tongue)
Cardiomegaly (increased size of heart than normal)
Chronic fatigue syndrome (disorder that causes extreme fatigue)

40-49:

Acquired cardiac septal defect (hole in the heart)
Alopecia (absence of hair from areas of the body)
Anger
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Back pain
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Confusional state
Crying
Drug ineffective

50-59:

Insomnia (sleeplessness)
Pain
Cystitis interstitial (unknown cause characterized by bladder pain)
Dizziness
Hyperhidrosis (abnormally increased sweating)
Narcolepsy (brain's inability to regulate sleep-wake cycles normally)
Somnolence (a state of near-sleep, a strong desire for sleep)
Abdominal pain
Drug ineffective
Pollakiuria (abnormally frequent passage of relatively small quantities or urine)

60+:

Fatigue (feeling of tiredness)
Oropharyngeal pain
Cardiomegaly (increased size of heart than normal)
Chronic kidney disease
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Dyspepsia (indigestion)
Echocardiogram abnormal
Emotional distress
Fall

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 49 people, 49.49%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 29 people, 29.29%
Hypersensitivity: 21 people, 21.21%
High Blood Pressure: 17 people, 17.17%
Ill-Defined Disorder: 11 people, 11.11%
Thrombosis (formation of a blood clot inside a blood vessel): 8 people, 8.08%
Back Pain: 8 people, 8.08%
Depression: 7 people, 7.07%
Pain: 7 people, 7.07%
Constipation: 6 people, 6.06%

* Approximation only. Some reports may have incomplete information.

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