Opana and Intestinal obstruction - a phase IV clinical study of FDA data

Summary:

Intestinal obstruction is reported as a side effect among people who take Opana (oxymorphone hydrochloride), especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months also take Oxycontin, and have Crohn's disease.

The phase IV clinical study analyzes which people have Intestinal obstruction when taking Opana. It is created by eHealthMe based on reports of 39,845 people who have side effects when taking Opana from the FDA, and is updated regularly.

What is Opana?

Opana has active ingredients of oxymorphone hydrochloride. It is often used in pain. eHealthMe is studying from 40,340 Opana users. Check the latest studies of Opana.

What is Intestinal obstruction?

Intestinal obstruction is found to be associated with 1,887 drugs and 2,613 conditions by eHealthMe. Check the latest studies of Intestinal obstruction.



On Jul, 11, 2026

39,845 people reported to have side effects when taking Opana.
Among them, 39 people (0.1%) have Intestinal obstruction.

Could Opana cause Intestinal obstruction?

Among these 39 people:

How long have people been on Opana when they have Intestinal obstruction? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 50 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 25 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 25 %
  • 10+ years: 0.0 %

What is the gender of people who have Intestinal obstruction when taking Opana? *

  • female: 61.54 %
  • male: 38.46 %

What is the age of people who have Intestinal obstruction when taking Opana? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 6.67 %
  • 30-39: 6.67 %
  • 40-49: 13.33 %
  • 50-59: 33.33 %
  • 60+: 40.0 %

What are other drugs people take besides Opana? *

  1. Dilaudid: 11 people, 28.21%
  2. Oxycontin: 11 people, 28.21%
  3. Sertraline: 6 people, 15.38%
  4. Humira: 5 people, 12.82%
  5. Premarin: 5 people, 12.82%
  6. Butrans: 4 people, 10.26%
  7. Ms Contin: 4 people, 10.26%
  8. Percocet: 4 people, 10.26%
  9. Morphine Sulfate: 4 people, 10.26%
  10. Prozac: 4 people, 10.26%

What are other side effects people have besides Intestinal obstruction? *

  1. Fatigue (feeling of tiredness): 11 people, 28.21%
  2. Constipation: 11 people, 28.21%
  3. Drug Dependence: 8 people, 20.51%
  4. Confusional State: 8 people, 20.51%
  5. Joint Pain: 8 people, 20.51%
  6. Drowsiness: 7 people, 17.95%
  7. Abdominal Discomfort: 7 people, 17.95%
  8. Abdominal Pain: 7 people, 17.95%
  9. Nausea (feeling of having an urge to vomit): 6 people, 15.38%
  10. Nausea And Vomiting: 6 people, 15.38%

What are the existing conditions these people have? *

  1. Osteoarthritis (a joint disease caused by cartilage loss in a joint): 4 people, 10.26%
  2. Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 4 people, 10.26%
  3. Flatulence (flatus expelled through the anus): 3 people, 7.69%
  4. Spinal Osteoarthritis (joint cartilage loss in spine): 2 people, 5.13%
  5. Scoliosis (a medical condition in which a person's spine is curved from side to side): 2 people, 5.13%
  6. Gastric Ulcer (stomach ulcer): 2 people, 5.13%
  7. High Blood Cholesterol: 2 people, 5.13%
  8. Vitamin B12 Deficiency: 1 person, 2.56%
  9. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 2.56%
  10. Arthritis (form of joint disorder that involves inflammation of one or more joints): 1 person, 2.56%

* Approximation only. Some reports may have incomplete information.

Do you take Opana and have Intestinal obstruction?

- Check whether Intestinal obstruction is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Opana:

Intestinal obstruction treatments and more:

How severe was Intestinal obstruction and when was it recovered:

Expand to all the drugs that have ingredients of oxymorphone hydrochloride:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Opana:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Intestinal obstruction:

Browse all the conditions that are associated with Intestinal obstruction:


How the study uses the data?

The study uses data from the FDA. It is based on oxymorphone hydrochloride (the active ingredients of Opana) and Opana (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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