Bydureon and Valtrex drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Bydureon (exenatide synthetic) and Valtrex (valacyclovir hydrochloride). Common drug interactions include swelling face among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Bydureon and Valtrex. It is created by eHealthMe based on reports of 32 people who take the same drugs from the FDA, and is updated regularly.

What is Bydureon?

Bydureon has active ingredients of exenatide synthetic. It is often used in type 2 diabetes. eHealthMe is studying from 24,309 Bydureon users. Check the latest studies of Bydureon.

What is Valtrex?

Valtrex has active ingredients of valacyclovir hydrochloride. It is often used in genital herpes. eHealthMe is studying from 39,999 Valtrex users. Check the latest studies of Valtrex.

On Jul, 30, 2026

32 people who take Bydureon and Valtrex together, and have interactions are studied.

What are the common drug interactions of Bydureon and Valtrex, by gender? *:

female:

Swelling face
Swollen tongue (swelling of tongue)
Hypokalaemia (low potassium)
Somnolence (a state of near-sleep, a strong desire for sleep)
Decreased appetite
Nausea (feeling of having an urge to vomit)
Weight decreased
Blood pressure increased
Bone cyst
Dysstasia (difficulty in standing)

male:

Chronic kidney disease
Fanconi syndrome acquired (self developed genetic disease of kidney damage due to defective transport system)
Bone density decreased
Blood glucose increased
Death
Fatigue (feeling of tiredness)
Injection site haemorrhage (bleeding from injection site)
Injection site nodule (small swelling or aggregation of cells in the body, esp. an abnormal one at injection site)
Injection site pain
Anhedonia (inability to experience pleasure from activities usually found enjoyable)

What are the common drug interactions of Bydureon and Valtrex, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Hypoaesthesia (reduced sense of touch or sensation)
Swelling face
Swollen tongue (swelling of tongue)

40-49:

Chronic kidney disease
Fanconi syndrome acquired (self developed genetic disease of kidney damage due to defective transport system)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Bone pain
Drug resistance (reduction in effectiveness of a drug)
Emotional distress
Gait disturbance
Pain
Renal impairment (severely reduced kidney function)

50-59:

Hypokalaemia (low potassium)
Somnolence (a state of near-sleep, a strong desire for sleep)
Decreased appetite
Malaise (a feeling of general discomfort or uneasiness)
Nausea (feeling of having an urge to vomit)
Pleurisy (inflammation of the pleurae, which causes pain when breathing)
Blood pressure increased
Arthralgia (joint pain)
Blood potassium decreased
Blood sodium decreased

60+:

Acute left ventricular failure (heart attack)
Blood glucose increased
Drug effect decreased
Drug ineffective
Dyspnoea (difficult or laboured respiration)
Dysstasia (difficulty in standing)
Fibromyalgia (a long-term condition which causes pain all over the body)
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Hypertensive heart disease
Muscular weakness (muscle weakness)

What are the existing conditions these people have? *

High Blood Cholesterol: 11 people, 34.38%
Diabetes: 11 people, 34.38%
High Blood Pressure: 9 people, 28.12%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 7 people, 21.88%
Depression: 7 people, 21.88%
Fibromyalgia (a long-term condition which causes pain all over the body): 7 people, 21.88%
Hypersensitivity: 6 people, 18.75%
Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 5 people, 15.62%
Pain: 5 people, 15.62%
Itching: 5 people, 15.62%

* Approximation only. Some reports may have incomplete information.

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