Byetta and Epipen drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Byetta (exenatide synthetic) and Epipen (epinephrine). Common drug interactions include decreased appetite among females and eye infection among males.

The phase IV clinical study analyzes what interactions people have when they take Byetta and Epipen. It is created by eHealthMe based on reports of 36 people who take the same drugs from the FDA, and is updated regularly.

What is Byetta?

Byetta has active ingredients of exenatide synthetic. It is often used in diabetes. eHealthMe is studying from 60,818 Byetta users. Check the latest studies of Byetta.

What is Epipen?

Epipen has active ingredients of epinephrine. It is often used in anaphylaxis. eHealthMe is studying from 23,760 Epipen users. Check the latest studies of Epipen.



On Jul, 27, 2026

36 people who take Byetta and Epipen together, and have interactions are studied.

Byetta and Epipen drug interactions.

What are the common drug interactions of Byetta and Epipen, by gender? *:

female:

  1. Decreased appetite
  2. Cholecystitis chronic (long lasting infection of gallbladder)
  3. Cholesterosis (abnormal deposition of cholesterol in tissues)
  4. Gallbladder disorder
  5. Injury
  6. Nausea (feeling of having an urge to vomit)
  7. Blood glucose decreased
  8. Blood glucose increased
  9. Asthma
  10. Chronic kidney disease

male:

  1. Eye infection
  2. Eye swelling
  3. Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
  4. Spinal cord injury
  5. Swelling
  6. Swelling face
  7. Urticaria (rash of round, red welts on the skin that itch intensely)
  8. Injection site haemorrhage (bleeding from injection site)
  9. Injection site reaction
  10. Local reaction (reaction of any substance at the site of use)

What are the common drug interactions of Byetta and Epipen, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Cholecystitis chronic (long lasting infection of gallbladder)
  2. Cholesterosis (abnormal deposition of cholesterol in tissues)
  3. Gallbladder disorder
  4. Injury

30-39:

  1. Hypoaesthesia oral (reduced sense of touch or sensation in mouth)
  2. Paraesthesia oral (sensation of tingling, tickling, prickling, pricking, or burning of a person's oral with no apparent long-term physical effect)
  3. Pruritus (severe itching of the skin)
  4. Rash
  5. Urticaria (rash of round, red welts on the skin that itch intensely)

40-49:

  1. Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)

50-59:

  1. Chronic kidney disease
  2. Blood glucose increased
  3. Decreased appetite
  4. Blood glucose decreased
  5. Drug ineffective
  6. Hypertension (high blood pressure)
  7. Loss of consciousness
  8. Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
  9. Pancreatic carcinoma metastatic (pancreatic cancer- metastatic)
  10. Tremor (trembling or shaking movements in one or more parts of your body)

60+:

  1. Nausea (feeling of having an urge to vomit)
  2. Decreased appetite
  3. Eye irritation
  4. Injection site pruritus (severe itching at injection site)
  5. Injury corneal
  6. Lung neoplasm malignant (cancer tumour of lung)
  7. Pleural effusion (water on the lungs)
  8. Rectocele (a bulging of the front wall of the rectum into the back wall of the vagina)
  9. Respiration (transport of oxygen from the outside air to the cells within tissues)
  10. Respiratory distress (difficulty in breathing)

What are the existing conditions these people have? *

  1. Type 2 Diabetes: 12 people, 33.33%
  2. Asthma: 8 people, 22.22%
  3. Hypersensitivity: 6 people, 16.67%
  4. Muscle Spasms (muscle contraction): 6 people, 16.67%
  5. Migraine (headache): 6 people, 16.67%
  6. Acne (skin problems that cause pimples): 5 people, 13.89%
  7. Premenstrual Syndrome: 5 people, 13.89%
  8. Pain: 5 people, 13.89%
  9. Birth Control: 4 people, 11.11%
  10. Stress And Anxiety: 4 people, 11.11%

* Approximation only. Some reports may have incomplete information.

Do you take Byetta and Epipen?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Byetta and Epipen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Byetta:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Epipen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Byetta and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Epipen and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on exenatide synthetic and epinephrine (the active ingredients of Byetta and Epipen, respectively), and Byetta and Epipen (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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