Caffeine and Vancomycin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Caffeine (caffeine) and Vancomycin (vancomycin). Common drug interactions include hypotension among females and drug hypersensitivity among males.

The phase IV clinical study analyzes what interactions people have when they take Caffeine and Vancomycin. It is created by eHealthMe based on reports of 41 people who take the same drugs from the FDA, and is updated regularly.

What is Caffeine?

Caffeine has active ingredients of caffeine. It is often used in fatigue. eHealthMe is studying from 6,667 Caffeine users. Check the latest studies of Caffeine.

What is Vancomycin?

Vancomycin has active ingredients of vancomycin. eHealthMe is studying from 17,165 Vancomycin users. Check the latest studies of Vancomycin.



On Jul, 31, 2026

41 people who take Caffeine and Vancomycin together, and have interactions are studied.

Caffeine and Vancomycin drug interactions.

What are the common drug interactions of Caffeine and Vancomycin, by gender? *:

female:

  1. Hypotension (abnormally low blood pressure)
  2. Bacteraemia (presence of bacteria in the blood)
  3. Device failure
  4. Hypoglycaemia (deficiency of glucose in the bloodstream)
  5. Small intestinal obstruction (blockage in small intestine)
  6. Abdominal pain
  7. Anaemia neonatal
  8. Neutropenia neonatal (an abnormally low number of neutrophils in below a month baby)
  9. Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
  10. Thrombocytopenia neonatal (decrease of platelets in blood in baby less than a month)

male:

  1. Drug hypersensitivity
  2. Toxic epidermal necrolysis (a rare, life-threatening skin condition that is usually caused by a reaction to drugs causes wide spread skin destruction)
  3. Mucosal inflammation (infection of mucous membrane)
  4. Hypogonadism (reduction or absence of hormone secretion or other physiological activity of the gonads (testes or ovaries))
  5. Developmental delay
  6. Klebsiella infection
  7. Klebsiella sepsis (klebsiella causes a potentially fatal whole-body inflammation)
  8. Endothelial dysfunction (compromise of normal function of endothelial cells leading to the inability of arteries and arterioles to dilate fully in response to an appropriate stimulus)
  9. Haemodynamic instability (disturbances in the blood movement in our body)
  10. Injection site necrosis (death of body tissue at injection site)

What are the common drug interactions of Caffeine and Vancomycin, by age (0-1 to 60+)? *:

0-1:

  1. Foetal growth restriction (poor growth of a baby while in the mother's womb during pregnancy)
  2. Low birth weight baby
  3. Maternal exposure before pregnancy (use of substance before pregnancy)
  4. Maternal exposure during pregnancy (use of substance during pregnancy)
  5. Muscle spasticity (tight or stiff muscles and an inability to control those muscles)
  6. Premature baby
  7. Small for dates baby (an unborn baby is growing more slowly and is smaller than most babies are at the same age)
  8. Anaemia neonatal
  9. Developmental delay
  10. Thrombocytopenia neonatal (decrease of platelets in blood in baby less than a month)

2-9:

n/a

10-19:

  1. Aplastic anaemia (blood disorder in which the body's bone marrow doesn't make enough new blood cells)
  2. Mucosal inflammation (infection of mucous membrane)
  3. Hypogonadism (reduction or absence of hormone secretion or other physiological activity of the gonads (testes or ovaries))

20-29:

  1. Gallbladder disorder
  2. Maternal exposure before pregnancy (use of substance before pregnancy)
  3. Maternal exposure during pregnancy (use of substance during pregnancy)
  4. Premature delivery
  5. Urticaria (rash of round, red welts on the skin that itch intensely)
  6. Aplastic anaemia (blood disorder in which the body's bone marrow doesn't make enough new blood cells)
  7. Appendicitis (inflammation of the appendix)

30-39:

n/a

40-49:

n/a

50-59:

  1. Drug hypersensitivity
  2. Toxic epidermal necrolysis (a rare, life-threatening skin condition that is usually caused by a reaction to drugs causes wide spread skin destruction)

60+:

  1. Bacteraemia (presence of bacteria in the blood)
  2. Device failure
  3. Hypoglycaemia (deficiency of glucose in the bloodstream)
  4. Hypotension (abnormally low blood pressure)
  5. Small intestinal obstruction (blockage in small intestine)
  6. Abdominal pain

What are the existing conditions these people have? *

  1. Lymphoma (cancer that begins in immune system cells): 9 people, 21.95%
  2. Acute Lymphocytic Leukaemia Recurrent (cancer in which the bone marrow makes too many lymphocytes-recurrent): 5 people, 12.20%
  3. Bone Marrow Conditioning Regimen: 5 people, 12.20%
  4. Depression: 5 people, 12.20%
  5. Diabetes: 5 people, 12.20%
  6. Pneumonia: 4 people, 9.76%
  7. Ill-Defined Disorder: 4 people, 9.76%
  8. Sepsis (a severe blood infection that can lead to organ failure and death): 4 people, 9.76%
  9. Erythema Multiforme (a type of hypersensitivity reaction): 4 people, 9.76%
  10. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 9.76%

* Approximation only. Some reports may have incomplete information.

Do you take Caffeine and Vancomycin?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Caffeine and Vancomycin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Caffeine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Vancomycin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Caffeine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Vancomycin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on caffeine and vancomycin (the active ingredients of Caffeine and Vancomycin, respectively), and Caffeine and Vancomycin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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